İnternal karotis darlığı olan hastalarda optik koherans tomografi-angio ile göz arka segment bulgularının değerlendirilmesi
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Tarih
2020
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Hatay Mustafa Kemal Üniversitesi
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info:eu-repo/semantics/openAccess
Özet
Amaç: Hafif-orta derecedeki internal karotis arter (İKA) darlığı olan hastaların retina kan akımı, optik disk kan akımı ve koroid kalınlanması üzerindeki etkisini optik koherens tomografi anjiyografi (OKTA) ile değerlendirmek ve elde edilen değerleri sağlıklı stenozu olmayan bireylerle karşılaştırmak. Gereç ve Yöntem: Bu bir prospektif çalışma olup toplam 75 katılımcı dahil edildi. IKA stenoz dercesine göre sağlıklı kontrol grup 1 (25 kişi), IKA darlığı %1- 49 olanlar grup 2 (25 kişi), İKA darlığı % 50-69 olanlar grup 3 (25 kişi) olarak değerlendirildi. Tüm katılımcılara en iyi düzeltilmiş görme keskinliği (EİDGK), göz içi basınç (GİB), ön segment, arka segment muayeneleri ve OKTA çekilip makular yüzeysel ve derin kapiller kan akış yoğunluğu, optik sinir baş kan akış yoğunluğu ve koroid kalınlığının verileri kaydedildi. Sonuçlar incelenerek karşılaştırıldı. Bulgular: Gruplar arasında karşılaştırma yapılıp incelendiğinde ortalama yüzeysel vasküler dansite, derin vasküler dansite, radyal peripapiller kapillerin (RPK) vasküler dansitesi ve koroid kalınlığında her üç grup arasında istatistiksel anlamlı farklılık görüldü (p<0,05). Yüzeysel kapiler pleksusun (YKP) tüm (46,48 ± 3,54) ve perifoveal alan vasküler dansitesi (47,18 ± 3,48) için grup 3'ün her iki gruptan farklı olduğu, YKP'nın parafoveal alan vasküler dansitesi (48,53 ± 5,09) için sadece grup 3 ile grup 1'in farklı olduğu görülmüştür (p<0,05). Derin kapiller pleksusun (DKP) tüm alan vasküler dansitesi (45,19 ± 5,67) için grup 3'ün her iki grupla farklı olduğu, DKP parafoveal (50,68 ± 4,26) ve perifoveal alan vasküler dansitesi (46,74 ± 5,78) için grup 3 ile grup 1'in farklı olduğu görülmektedir (p<0,05). RPK'nın Tüm disk vasküler dansitesinde (47,61 ± 2,18) grup 3'ün her iki gruptan farklı olduğu görüldü (p<0,05). Subfoveal koroid kalınlığı (212,25 ± 23,42) açısından grup 3'ün her iki gruptan farklı olduğu görüldü. Koroid nazal (145,05 ± 22,47) ve koroid temporal parametrelerinde (167,50 ± 23,11) grup 3'ün hem grup 1 hem grup 2'den farklı olduğu görüldü (p<0,05). Fovea-parafoveal-perifoveal parametrelerinin gruplara göre dağılımı incelendiğinde hiçbir değişkende anlamlı bir farklılık görülmemiştir. Sonuç: Orta derece İKA stenozu olan hastalar sağlıklı kontrollerle karşılaştırıldığında yüzeyel/derin vasküler dansite ve RPK tabakasında azalmış vasküler yoğunluk ve koroidde incelme olduğu tespit edildi.
Purpose: To evaluate the effect of patients with mild to moderate internal carotid artery (ICA) stenosis on retinal blood flow, optic disc blood flow and choroid thickening with optic coherence tomography angiography (OCTA) and compare the obtained values with individuals without healthy stenosis. Material and Method: This is a prospective study, with a total of 75 participants included. According to IKA stenosis grade, healthy control group 1 (25 people), IKA stenosis 1-49% were group 2 (25 people), and IKA stenosis 50-69% were group 3 (25 people). The best corrected visual acuity (EIDGK), intraocular pressure (IOP), anterior segment, posterior segment examinations, and OCTA were taken to all participants, and macular superficial and deep capillary blood flow density, optic nerve head blood flow density, and choroidal thickness data were recorded. The results were examined and compared. Results: When compared and analyzed between groups there was a statistically significant difference between the three groups in mean superficial vascular density, deep vascular density, vascular density of Radial Peripaller Capillary (RPC) and choroid thickness (p <0.05). It was observed that group 3 was different from both groups for the whole (46,48 ± 3,54) and perifoveal area vascular density (47,18 ± 3,48) of the superficial capillary plexus (SCP), only group 3 and group 1 were different for the parafoveal area (48,53 ± 5,09) of SCP (p <0.05). It is seen that the deep capillary plexus (DCP) group 3 for the whole area vascular density (45,19 ± 5,67) is different with both groups, and group 3 and group 1 are different for DCP parafoveal (50,68 ± 4,26) and perifoveal area vascular density (46,74 ± 5,78) (p <0.05). It was observed that group 3 of RPC was different from both groups in the whole disc vascular density (47,61 ± 2,18) (p <0.05). In terms of subfoveal choroid thickness (212,25 ± 23,42), group 3 was found to be different from both groups (p <0.05). It was seen that group 3 was different from both group 1 and group 2 in choroidal nasal (145,05 ± 22,47) and choroidal temporal parameters (167,50 ± 23,11) (p <0.05). When the distribution of fovea-parafoveal-perifoveal parameters by groups was examined, no significant difference was observed in any variables. Conclusion: Compared to healthy controls, patients with moderate ICA stenosis revealed superficial / deep vascular density and decreased vascular density in the RPK layer and thinning in the choroid. Key words: Internal carotid artery stenosis, optic coherence tomography angiography, choroid, retinal vascular density.
Purpose: To evaluate the effect of patients with mild to moderate internal carotid artery (ICA) stenosis on retinal blood flow, optic disc blood flow and choroid thickening with optic coherence tomography angiography (OCTA) and compare the obtained values with individuals without healthy stenosis. Material and Method: This is a prospective study, with a total of 75 participants included. According to IKA stenosis grade, healthy control group 1 (25 people), IKA stenosis 1-49% were group 2 (25 people), and IKA stenosis 50-69% were group 3 (25 people). The best corrected visual acuity (EIDGK), intraocular pressure (IOP), anterior segment, posterior segment examinations, and OCTA were taken to all participants, and macular superficial and deep capillary blood flow density, optic nerve head blood flow density, and choroidal thickness data were recorded. The results were examined and compared. Results: When compared and analyzed between groups there was a statistically significant difference between the three groups in mean superficial vascular density, deep vascular density, vascular density of Radial Peripaller Capillary (RPC) and choroid thickness (p <0.05). It was observed that group 3 was different from both groups for the whole (46,48 ± 3,54) and perifoveal area vascular density (47,18 ± 3,48) of the superficial capillary plexus (SCP), only group 3 and group 1 were different for the parafoveal area (48,53 ± 5,09) of SCP (p <0.05). It is seen that the deep capillary plexus (DCP) group 3 for the whole area vascular density (45,19 ± 5,67) is different with both groups, and group 3 and group 1 are different for DCP parafoveal (50,68 ± 4,26) and perifoveal area vascular density (46,74 ± 5,78) (p <0.05). It was observed that group 3 of RPC was different from both groups in the whole disc vascular density (47,61 ± 2,18) (p <0.05). In terms of subfoveal choroid thickness (212,25 ± 23,42), group 3 was found to be different from both groups (p <0.05). It was seen that group 3 was different from both group 1 and group 2 in choroidal nasal (145,05 ± 22,47) and choroidal temporal parameters (167,50 ± 23,11) (p <0.05). When the distribution of fovea-parafoveal-perifoveal parameters by groups was examined, no significant difference was observed in any variables. Conclusion: Compared to healthy controls, patients with moderate ICA stenosis revealed superficial / deep vascular density and decreased vascular density in the RPK layer and thinning in the choroid. Key words: Internal carotid artery stenosis, optic coherence tomography angiography, choroid, retinal vascular density.
Açıklama
Anahtar Kelimeler
Göz Hastalıkları, Eye Diseases, İnternal karotis arter darlığı, optik koherens tomografi anjiyografi, koroid, retinal vasküler yoğunluk.
