Colchicine related pancytopenia unresponsive to granulocyte colony stimulating factor

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dc.authorscopusid15761068100
dc.authorscopusid15759394500
dc.authorscopusid15759548500
dc.authorscopusid15760987600
dc.contributor.authorSedat, Kaya
dc.contributor.authorAlper, Kararmaz
dc.contributor.authorHaktan, Karaman
dc.contributor.authorSelim, Turhanoglu
dc.date.accessioned2024-09-19T15:45:35Z
dc.date.available2024-09-19T15:45:35Z
dc.date.issued2007
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: Colchicine overdose is uncommon but extremely serious and it is associated with considerable mortality. Previous reports have shown that granulocyte colony-stimulating factor therapy was an effective method of treating the colchicine related pancytopenia. Case Reports: We describe a case of suicidal ingestion of 15 mg of colchicine in a previously healthy 23-yearsold woman. During nasogastric tube insertion, nasal bleeding developed in the emergency room and stopped after anterior nasal tamponage. Following days, patient's platelet counts decreased to 14.9 K/UL due to bone marrow suppression. In spite of all therapeutic approach including granulocyte colony-stimulating factor, our patient died on 5th day due to severe bleeding. Conclusions: Bone marrow suppression may be resistant to granulocyte colony-stimulating factor in colchicine poisoning. We recommend that all invasive procedures were performed more carefully in patient doubted colchicine ingestion.en_US
dc.identifier.endpage15en_US
dc.identifier.issn1643-3742
dc.identifier.scopus2-s2.0-33846067759en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage13en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14786
dc.identifier.volume8en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofCase Reports and Clinical Practice Reviewen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectColchicineen_US
dc.subjectGranulocyte colony-stimulating factoren_US
dc.subjectIntoxicationen_US
dc.titleColchicine related pancytopenia unresponsive to granulocyte colony stimulating factoren_US
dc.typeArticleen_US

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