A new treatment approach in tuberculosis
[ N/A ]
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Medi+World Int
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Role of total excision of lymphadenopathies (LAPs) if they are limited in number is unknown in the treatment of tuberculosis (TB). A 14-year old male applied with weight loss. On physical examination, there were multiple right axillary LAPs with sizes of 3x2 cm. In laboratory examination, C-reactive protein (CRP) was 2.1 mg/dL, erythrocyte sedimentation rate (ESR) was 73 mm/hr, and lactate dehydrogenase (LDH) was 250 IU/L. Tuberculin skin test showed a 22 mm of induration. The right axillary LAPs were excised, totally, and histological examination demonstrated granulomas with Langhans-type giant histiocytes. After the operation, ESR, CRP, and LDH values and his weight returned to normal without any treatment. Secondly, a 43year old female applied with fever, night sweats, and weight loss. On physical examination, there were multiple and conglomerated left axillary LAPs with sizes of 6x4 cm. In laboratory examination, CRP was 5.2 mg/dL, ESR was 74 mm/hr, and LDH was 329 IU/L. Tuberculin skin test showed a 20 mm of induration. The LAPs were excised, totally, and histological examination demonstrated granulomatous lymphadenitis with epitheloid histiocytes, Langhanstype giant cells, and caseified necrosis. After the operation, fever and night sweats disappeared, and CRP, ESR, and LDH values were normalized. She returned to normal weight within two months without any antituberculous treatment. As a conclusion, total excision of LAPs if they are limited in number may both have a diagnostic and curative role in TB, probably by decreasing large numbers of bacteria, so remaining small numbers can be eliminated by immune system, alone.
Açıklama
Anahtar Kelimeler
Tuberculosis, total lymph node excision
Kaynak
World Family Medicine
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
11
Sayı
10
