A new treatment approach in tuberculosis

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dc.contributor.authorHelvaci, Mehmet Rami
dc.contributor.authorAkkucuk, Seckin
dc.contributor.authorAydogan, Akin
dc.date.accessioned2024-09-18T21:00:24Z
dc.date.available2024-09-18T21:00:24Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractRole of total excision of lymphadenopathies (LAPs) if they are limited in number is unknown in the treatment of tuberculosis (TB). A 14-year old male applied with weight loss. On physical examination, there were multiple right axillary LAPs with sizes of 3x2 cm. In laboratory examination, C-reactive protein (CRP) was 2.1 mg/dL, erythrocyte sedimentation rate (ESR) was 73 mm/hr, and lactate dehydrogenase (LDH) was 250 IU/L. Tuberculin skin test showed a 22 mm of induration. The right axillary LAPs were excised, totally, and histological examination demonstrated granulomas with Langhans-type giant histiocytes. After the operation, ESR, CRP, and LDH values and his weight returned to normal without any treatment. Secondly, a 43year old female applied with fever, night sweats, and weight loss. On physical examination, there were multiple and conglomerated left axillary LAPs with sizes of 6x4 cm. In laboratory examination, CRP was 5.2 mg/dL, ESR was 74 mm/hr, and LDH was 329 IU/L. Tuberculin skin test showed a 20 mm of induration. The LAPs were excised, totally, and histological examination demonstrated granulomatous lymphadenitis with epitheloid histiocytes, Langhanstype giant cells, and caseified necrosis. After the operation, fever and night sweats disappeared, and CRP, ESR, and LDH values were normalized. She returned to normal weight within two months without any antituberculous treatment. As a conclusion, total excision of LAPs if they are limited in number may both have a diagnostic and curative role in TB, probably by decreasing large numbers of bacteria, so remaining small numbers can be eliminated by immune system, alone.en_US
dc.identifier.doi10.5742/MEFM.2014.92435
dc.identifier.endpage36en_US
dc.identifier.issn1839-0188
dc.identifier.issn1839-0196
dc.identifier.issue10en_US
dc.identifier.startpage33en_US
dc.identifier.urihttps://doi.org/10.5742/MEFM.2014.92435
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12664
dc.identifier.volume11en_US
dc.identifier.wosWOS:000421847600006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherMedi+World Inten_US
dc.relation.ispartofWorld Family Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTuberculosisen_US
dc.subjecttotal lymph node excisionen_US
dc.titleA new treatment approach in tuberculosisen_US
dc.typeArticleen_US

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