Usefulness of (1?3)-b-D glucan in early diagnosing Pneumocystis jirovecii pneumonia: A case report

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dc.authorscopusid37101026900
dc.authorscopusid8410689800
dc.authorscopusid25639501700
dc.authorscopusid36477499400
dc.authorscopusid55964756500
dc.authorscopusid6603662687
dc.contributor.authorAtalay, Mustafa Altay
dc.contributor.authorKoc, Ayse Nedret
dc.contributor.authorKaynar, Leyla Gul
dc.contributor.authorInci, Melek
dc.contributor.authorTekinsen, Fatma Filiz Kasap
dc.contributor.authorEser, Bulent
dc.date.accessioned2024-09-19T15:49:50Z
dc.date.available2024-09-19T15:49:50Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPneumocystis jirovecii pneumoniae (PJP) may be difficult to diagnose. Since pneumocystis cannot be cultured, the diagnosis of PJP requires microscopic examination to identify pneumocystis from induced sputum or bronchoalveolar lavage (BAL) fluid. In order to evaluate the usefulness of (1{squared times}3) ß- D-glucan (BDG) levels in the early diagnosis of PJP, we describe the case of PJP in a 25-year-old male with acute lymphoblastic leukaemia (ALL) admitted to hospital with progressive dyspnea and fever with chills. The patient was not infected with human immunodeficiency virus (HIV). Sputum, blood, and urine cultures were negative; smears for acid-fast bacilli and tests for viral antibodies were both negative. The microbiology study of the BAL with Giemsa and immunofluorescence staining, seven days after admission showed the existence of P. jiroveci in the lungs. Further, one day and five days after admission, (1{squared times}3) ß-D-glucan (BDG) levels were very high. The high serum level of BDG considerably decreased after treatment with trimethoprim-sulfamethoxazole (TMPSMX) and the clinical condition of the patient increasingly improved.en_US
dc.identifier.endpage61en_US
dc.identifier.issn1124-9390
dc.identifier.issue1en_US
dc.identifier.pmid24651093en_US
dc.identifier.scopus2-s2.0-84897458967en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage57en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/15442
dc.identifier.volume22en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEDIMES Edizioni Medico Scientificheen_US
dc.relation.ispartofInfezioni in Medicinaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbeta-Glucansen_US
dc.subjectEarly Diagnosisen_US
dc.subjectHumansen_US
dc.subjectMaleen_US
dc.subjectPneumocystis jiroveciien_US
dc.subjectPneumonia, Pneumocystisen_US
dc.subjectYoung Adulten_US
dc.subjectaminophyllineen_US
dc.subjectbeta 1, 3 glucanen_US
dc.subjectcefepimeen_US
dc.subjectclarithromycinen_US
dc.subjectcotrimoxazoleen_US
dc.subjectdexamethasoneen_US
dc.subjectgranulocyte colony stimulating factoren_US
dc.subjectlevofloxacinen_US
dc.subjectunclassified drugen_US
dc.subjectbeta glucanen_US
dc.subjectbeta-1,3-D-glucanen_US
dc.subjectadulten_US
dc.subjectarticleen_US
dc.subjectcase reporten_US
dc.subjectdyspneaen_US
dc.subjectfeveren_US
dc.subjectfollow upen_US
dc.subjectGiemsa stainen_US
dc.subjecthumanen_US
dc.subjecthuman tissueen_US
dc.subjectimmunofluorescence testen_US
dc.subjectlung lavageen_US
dc.subjectlung mycosisen_US
dc.subjectmaleen_US
dc.subjectmyeloid leukemiaen_US
dc.subjectneutropeniaen_US
dc.subjectoxygen therapyen_US
dc.subjectPneumocystis jirovecien_US
dc.subjectwheezingen_US
dc.subjectyoung adulten_US
dc.subjectblooden_US
dc.subjectearly diagnosisen_US
dc.subjectPneumonia, Pneumocystisen_US
dc.titleUsefulness of (1?3)-b-D glucan in early diagnosing Pneumocystis jirovecii pneumonia: A case reporten_US
dc.title.alternativeUtilità del (1?3)-b-D glucano nella diagnosi precoce di polmonite da Pneumocystis jirovecii: Un caso clinicoen_US
dc.typeArticleen_US

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