YKL-40 and fibronectin levels in patients with placentalinvasion anomaly

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dc.contributor.authorKarapınar, Oya Soylu
dc.contributor.authorŞahin, Hanifi
dc.contributor.authorGözükara, İlkay
dc.contributor.authorŞahin, Eda Adeviye
dc.contributor.authorGöngören, Arif
dc.contributor.authorSezgin, Burak
dc.contributor.authorÖzcan, Oğuzhan
dc.date.accessioned2024-09-19T16:26:48Z
dc.date.available2024-09-19T16:26:48Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim: To investigate the level of YKL-40 and fibronectin in patients with total placenta previa and to evaluate the presence of placental invasion anomaly such as accreta.Materials and Methods: A total of 60 patients were included in this prospective study. The patients were classified according to the placental localization as assessed through ultrasound. The study group consisted of 33 patients diagnosed with placenta previa or accreta with previous cesarean section. These patients were also subdivided into two groups according to the histopathological examination results as invasion-positive group and invasion-negative group. The control group consisted of 27 patients who were admitted to the gynecology clinic with previous cesarean deliveries and had normal placental localization. Serum YKL-40 and fibronectin levels were measured in two groups via human chitinase-3-like protein 1 (Ykl-40/CHI3L1) and fibronectin enzyme-linked immunosorbent assay kits.Results: Mean serum levels for YKL-40 and fibronectin were similar between the study and control groups. In the subgroup analysis according to invasion anomaly, the level of YKL-40 in invasion-positive group (n=11) was higher than invasion-negative group (n=22), indicating a statistically significant difference.Conclusion: Outcomes of this research indicates that YKL-40 can be used as a marker for identifying placental invasion anomalies.en_US
dc.identifier.doi10.5455/annalsmedres.2020.06.622
dc.identifier.endpage1444en_US
dc.identifier.issn2636-7688
dc.identifier.issue8en_US
dc.identifier.startpage1440en_US
dc.identifier.trdizinid459504en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2020.06.622
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/459504
dc.identifier.urihttps://hdl.handle.net/20.500.12483/16359
dc.identifier.volume28en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleYKL-40 and fibronectin levels in patients with placentalinvasion anomalyen_US
dc.typeOtheren_US

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