Investigation into the frequency of helicobacter pylori infection with carbon 14 urea breath test in patients with vitiligo

dc.contributor.authorRifaioğlu, Emine Nur
dc.contributor.authorAydoğan, Füsun
dc.contributor.authorŞen Bülbül, Bilge
dc.contributor.authorŞen, Tuğba
dc.contributor.authorEkiz, Özlem
dc.date.accessioned2019-07-16T15:55:34Z
dc.date.available2019-07-16T15:55:34Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground/aim: Vitiligo is a common, acquired depigmenting skin disorder. The relationship between Helicobacter pylori (HP) infection and autoimmune dermatological disease has been previously reported. However, the frequency of HP infection in patients with vitiligo has not been reported. In this study, we aimed to investigate the frequency of HP infection with the carbon 14 (C14) urea breath test (UBT) in patients with vitiligo. Materials and methods: This study included 34 patients (18 males and 16 females) with vitiligo and 30 age- and sex-matched healthy controls. HP infection was diagnosed using the C14 UBT (Heliprobe). Statistical analysis was performed using SPSS 19. Results: The frequency of HP infection was 64.7% in the patient group and 33.3% in the control group according to the C14 UBT (chisquare test, P = 0.012). HP infection frequency is statistically significantly higher in patients with vitiligo. Conclusion: To the best of our knowledge, this is the first investigation of the frequency of HP positivity in patients with vitiligo. To better understand the role of HP in vitiligo as an etiological or initiating factor, further experimental and clinical studies with a greater number of patients are needed.en_US
dc.description.abstractBackground/aim: Vitiligo is a common, acquired depigmenting skin disorder. The relationship between Helicobacter pylori (HP) infection and autoimmune dermatological disease has been previously reported. However, the frequency of HP infection in patients with vitiligo has not been reported. In this study, we aimed to investigate the frequency of HP infection with the carbon 14 (C14) urea breath test (UBT) in patients with vitiligo. Materials and methods: This study included 34 patients (18 males and 16 females) with vitiligo and 30 age- and sex-matched healthy controls. HP infection was diagnosed using the C14 UBT (Heliprobe). Statistical analysis was performed using SPSS 19. Results: The frequency of HP infection was 64.7% in the patient group and 33.3% in the control group according to the C14 UBT (chisquare test, P = 0.012). HP infection frequency is statistically significantly higher in patients with vitiligo. Conclusion: To the best of our knowledge, this is the first investigation of the frequency of HP positivity in patients with vitiligo. To better understand the role of HP in vitiligo as an etiological or initiating factor, further experimental and clinical studies with a greater number of patients are needed.en_US
dc.identifier.endpage1054en_US
dc.identifier.issn1300-0144
dc.identifier.issue6en_US
dc.identifier.pmid25552160en_US
dc.identifier.scopus2-s2.0-84908075504en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1051en_US
dc.identifier.urihttps://trdizin.gov.tr/publication/paper/detail/TWpFek1qSXlNZz09
dc.identifier.urihttps://hdl.handle.net/20.500.12483/2093
dc.identifier.volume44en_US
dc.identifier.wosWOS:000344155900021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCerrahien_US
dc.titleInvestigation into the frequency of helicobacter pylori infection with carbon 14 urea breath test in patients with vitiligoen_US
dc.typeArticleen_US

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