The relationship between serum vitamin d and bare-metal in-stent restenosis in patients with stable coronary artery disease

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dc.contributor.authorKurtul, Alparslan
dc.contributor.authorGök, Murat
dc.contributor.authorÖrnek, Ender
dc.date.accessioned2024-09-19T16:22:13Z
dc.date.available2024-09-19T16:22:13Z
dc.date.issued2020
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim: It has been shown that low levels of vitamin D are associated with increased cardiovascular risk factors and adverse events. The relationship between serum vitamin D level and bare-metal stent in-stent restenosis was investigated in our study. Material and Methods: A total of 181 patients with stable coronary artery disease and previously implanted (>3 months) bare-metal stent were included in the study. Two groups were formed according to angiographic results as Group 1 (?50% in-stent stenosis) and Group 2 (<50% in-stent stenosis). Serum vitamin D measurements were performed by reverse-phase HPLC. Results: The mean serum vitamin D levels were found to be significantly lower in Group 1 compared to Group 2 (17.7 ± 5.3 ng/ml and 20.9 ± 6.7 ng/ml, p<0.01, respectively) and length of stent was longer in Group 1 compared to Group 2 (18.7 ± 5.3 mm and 17.1 ± 11.2 mm, p<0.01, respectively). In multivariate logistic regression analysis, only low level of serum vitamin D and stent length were independent risk factors for bare-metal in-stent stenosis. Conclusion: Low level of vitamin D might be related to fibrosis and inflammation resulting in in-stent stenosis. Further studies are warranted to determine whether vitamin D supplementation could prevent progression of stent re-stenosis.en_US
dc.identifier.doi10.18663/tjcl.624722
dc.identifier.endpage242en_US
dc.identifier.issn2149-8296
dc.identifier.issue4en_US
dc.identifier.startpage237en_US
dc.identifier.trdizinid477929en_US
dc.identifier.urihttps://doi.org/10.18663/tjcl.624722
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/477929
dc.identifier.urihttps://hdl.handle.net/20.500.12483/15706
dc.identifier.volume11en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Clinics and Laboratoryen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe relationship between serum vitamin d and bare-metal in-stent restenosis in patients with stable coronary artery diseaseen_US
dc.typeArticleen_US

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