Antioxidant and Cytotoxic Activities of Fumaria parviflora Lam. and Fumaria capreolata L.

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dc.contributor.authorCELIK, Tulay Askin
dc.contributor.authorASLANTURK, Ozlem Sultan
dc.contributor.authorYILMAZ, Ebru Sebnem
dc.contributor.authorGUZEL, Yelda
dc.date.accessioned2024-09-18T19:47:57Z
dc.date.available2024-09-18T19:47:57Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThis study was carried out to examine the in vitro antioxidant and cytotoxic effects of methanol extracts of Fumaria parviflora Lam. and Fumaria capreolata. Antioxidant assays carried out by employing 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and phosphomolybdate assays. Cell viability was quantified by employing MTT assay for 24, 48 and 72 h of exposures to 25-250 mu gmL(-1) concentrations of the extracts. F. parviflora methanol extract possessed the highest antioxidant activities in both free DPPH scavenging and total antioxidant capacity assays. Results from MTT assay revealed that F. capreolata methanol extract significantly increased the cell proliferation in human hepatocellular carcinoma (Hep3B) cells after 24 and 48 hours of treatment. After 72 hours of treatment, methanol extract slightly inhibited the proliferation of Hep3B cell lines, in a time-and dose-dependent manner. While F. parviflora extract had the highest cytotoxic effect on Hep3B cells after 72 hours of the treatment. F. capreolata did not cause any significant cytotoxic effect on these cell lines.en_US
dc.description.sponsorshipHMKU Scientific Research Project Fund [18.YL.010]en_US
dc.description.sponsorshipThis study was partly supported by HMKU Scientific Research Project Fund (18.YL.010).en_US
dc.identifier.doi10.18016/ksutarimdoga.vi.899937
dc.identifier.endpage827en_US
dc.identifier.issn2619-9149
dc.identifier.issue4en_US
dc.identifier.startpage819en_US
dc.identifier.trdizinid1117432en_US
dc.identifier.urihttps://doi.org/10.18016/ksutarimdoga.vi.899937
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1117432
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7240
dc.identifier.volume25en_US
dc.identifier.wosWOS:000822800300019en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherKahramanmaras Sutcu Imam Univ Rektorluguen_US
dc.relation.ispartofKsu Tarim Ve Doga Dergisi-Ksu Journal of Agriculture and Natureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject1,1-diphenyl-2-picrylhydrazylen_US
dc.subjectAntioxidant activityen_US
dc.subjectCytotoxicityen_US
dc.subjectFumaria parvifloraen_US
dc.subjectFumaria capreolataen_US
dc.titleAntioxidant and Cytotoxic Activities of Fumaria parviflora Lam. and Fumaria capreolata L.en_US
dc.typeArticleen_US

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