Hepatitis C virus genotypes in Adana and Antakya regions of Turkey*

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dc.contributor.authorÖztürk, Agah Bahadır
dc.contributor.authorDoğan, Ümit Bilge
dc.contributor.authorÖztürk Akçaer, Nevin
dc.contributor.authorÖzyazıcı, Gonca
dc.contributor.authorDemir, Mehmet
dc.contributor.authorAkın, Mustafa Salih
dc.contributor.authorBingöl, Ali Süha
dc.date.accessioned2019-07-16T16:00:20Z
dc.date.available2019-07-16T16:00:20Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground/aim: Hepatitis C virus (HCV) genotype 1 was found to be dominant in Turkey. In this study, HCV genotypes were examined in the Adana and Antakya regions of Turkey. Materials and methods: The study consisted of 639 HCV-RNA–positive patients with chronic HCV infection in Adana (214 males and 101 females) and Antakya (139 males and 185 females) in Turkey. Real time-polymerase chain reaction was used for genotype determination. Results: In Antakya, it was determined that the percentages of genotypes of type 1a (0.31%), 1b (86.73%), 2 (9.26%), 3 (0.93%), and 4 (2.78%) were compatible with the nationwide results seen in Turkey. In Adana, the percentages of genotypes of type 1a (3.49%), 1b (55.24%), 2 (14.60%), 3 (26.03%), and 4 (0.63%) were found to be different. This difference was mainly due to the infection rates in males: genotype 1b was significantly lower (42.5% versus 82.2%, P < 0.001) in men in Adana, but genotype 2 (17.8% versus 7.9%, P = 0.021) and genotype 3 (34.6% versus 7.9%, P < 0.001) were significantly higher in men than in women in Adana. Conclusion: Rates of genotypes 2 and 3 were unexpectedly high in Adana compared to other parts of Turkeyen_US
dc.description.abstractBackground/aim: Hepatitis C virus (HCV) genotype 1 was found to be dominant in Turkey. In this study, HCV genotypes were examined in the Adana and Antakya regions of Turkey. Materials and methods: The study consisted of 639 HCV-RNA–positive patients with chronic HCV infection in Adana (214 males and 101 females) and Antakya (139 males and 185 females) in Turkey. Real time-polymerase chain reaction was used for genotype determination. Results: In Antakya, it was determined that the percentages of genotypes of type 1a (0.31%), 1b (86.73%), 2 (9.26%), 3 (0.93%), and 4 (2.78%) were compatible with the nationwide results seen in Turkey. In Adana, the percentages of genotypes of type 1a (3.49%), 1b (55.24%), 2 (14.60%), 3 (26.03%), and 4 (0.63%) were found to be different. This difference was mainly due to the infection rates in males: genotype 1b was significantly lower (42.5% versus 82.2%, P < 0.001) in men in Adana, but genotype 2 (17.8% versus 7.9%, P = 0.021) and genotype 3 (34.6% versus 7.9%, P < 0.001) were significantly higher in men than in women in Adana. Conclusion: Rates of genotypes 2 and 3 were unexpectedly high in Adana compared to other parts of Turkeyen_US
dc.identifier.endpage665en_US
dc.identifier.issn1300-0144
dc.identifier.issue4en_US
dc.identifier.pmid25551939en_US
dc.identifier.scopus2-s2.0-84901037093en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage661en_US
dc.identifier.urihttps://trdizin.gov.tr/publication/paper/detail/TWpFek1UUXdNQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12483/2252
dc.identifier.volume44en_US
dc.identifier.wosWOS:000336959100022en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCerrahien_US
dc.titleHepatitis C virus genotypes in Adana and Antakya regions of Turkey*en_US
dc.typeArticleen_US

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