Conjunctival Impression Cytology and Tear Function in Patients with Keratoconus

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dc.contributor.authorÖzcan, Deniz Özarslan
dc.contributor.authorÖzcan, Sait Coşkun
dc.contributor.authorGürsoy, Didar
dc.date.accessioned2024-09-19T16:21:01Z
dc.date.available2024-09-19T16:21:01Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjectives: The aim of this study was to evaluate the ocular surface alterations of conjunctival cytological changes and tear function in patients with keratoconus. Methods: A total of 98 eyes with keratoconus and 68 eyes of age- and sex- matched healthy subjects were included in this prospective study. Ophthalmological evaluations, including Ocular Surface Disease Index (OSDI), tear break-up time (TBUT), ocular surface staining (OSS), Schirmer test, and conjunctival impression cytology (CIC), were performed. Results: The mean participant age was 23.4±5.3 years in the keratoconus group and 24.9±6.0 years in the control group. In the keratoconus group, the mean OSDI and OSS scores were statistically significantly higher than those of the controls, and the Schirmer and TBUT results were statistically significantly lower (all p<0.001). The severity of keratoconus was positively correlated with the CIC grade (r=0.292; p=0.004). Conclusion: Keratoconus results in deterioration of the ocular surface, including CIC and tear function parameters. The grade of keratoconus appears to be associated with conjunctival cytologic changes.en_US
dc.identifier.doi10.14744/bej.2021.83584
dc.identifier.endpage83en_US
dc.identifier.issn2459-1777
dc.identifier.issn2587-0394
dc.identifier.issue2en_US
dc.identifier.startpage79en_US
dc.identifier.trdizinid476453en_US
dc.identifier.urihttps://doi.org/10.14744/bej.2021.83584
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/476453
dc.identifier.urihttps://hdl.handle.net/20.500.12483/15522
dc.identifier.volume6en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofBEYOGLU EYE JOURNALen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleConjunctival Impression Cytology and Tear Function in Patients with Keratoconusen_US
dc.typeArticleen_US

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