Biomechanic and biochemical analysis of the effects of local Ankaferd Blood Stopper® application on osseointegration of titanium implants

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dc.contributor.authorÖzcan, Erhan Cahit
dc.contributor.authorÖzdemir, Hasan Emre
dc.contributor.authorGül, Mehmet
dc.contributor.authorTanık, Abdulsamet
dc.contributor.authorYıldırım, Tuba Talo
dc.contributor.authorBozoğlan, Alihan
dc.contributor.authorDündar, Serkan
dc.date.accessioned2024-09-19T16:26:49Z
dc.date.available2024-09-19T16:26:49Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim: Investigations into Ankaferd Blood Stopper® (ABS) on bone healing have revealed positive bone regeneration effects. The exact mechanism of this positive bone tissue metabolism effect is unknown. This study’s aim is a biomechanic and biochemical investigation of the effects of local ABS application on the osseointegration of titanium implants. Methodology: Sprague Dawley rats were divided into four groups of ten rats each. The control group (n=20) received no treatment during the experimental period, while the ABS group (n=20) had ABS applied locally during the surgical application of the titanium implant before insertion into the bone sockets. After 2 (controls n=10 and ABS n=10) and 4 weeks (controls n=10 and ABS n=10) experimental periods, the rats were sacrificed and implants with surrounding bone tissues were removed for reverse torque analysis (Newton), blood sample collection, and biochemical analysis. Results: The biomechanic bone implant contact ratio detected was higher in week 4 than in week 2 in the ABS group (p<0, 05). Lower phosphor levels were detected in the ABS group than in the 4-week controls (p<0, 05). Conclusion: According to the biomechanical parameters, ABS is more effective after four weeks than after two weeks when locally applied.en_US
dc.identifier.doi10.5577/intdentres.2022.vol12.no1.5
dc.identifier.endpage33en_US
dc.identifier.issn2146-1767
dc.identifier.issue1en_US
dc.identifier.startpage27en_US
dc.identifier.trdizinid1123964en_US
dc.identifier.urihttps://doi.org/10.5577/intdentres.2022.vol12.no1.5
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1123964
dc.identifier.urihttps://hdl.handle.net/20.500.12483/16394
dc.identifier.volume12en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofInternational Dental Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleBiomechanic and biochemical analysis of the effects of local Ankaferd Blood Stopper® application on osseointegration of titanium implantsen_US
dc.typeArticleen_US

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