Increased epicardial fat tissue is a marker of subclinical atherosclerosis in patients with psoriasis

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dc.authoridKARTAL, ISMAIL/0000-0002-8847-5806
dc.contributor.authorSen, B. Bulbul
dc.contributor.authorAtci, N.
dc.contributor.authorRifaioglu, E. N.
dc.contributor.authorEkiz, O.
dc.contributor.authorKartal, I.
dc.contributor.authorBuyukkaya, E.
dc.contributor.authorKurt, M.
dc.date.accessioned2024-09-18T21:05:13Z
dc.date.available2024-09-18T21:05:13Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackgroundCarotid intima-media thickness (CIMT) is a potential indicator of subclinical atherosclerosis in patients with psoriasis. Epicardial fat thickness (EFT) is proposed as a new cardiometabolic risk factor. ObjectiveTo evaluate the association between EFT and CIMT in patients with psoriasis. MethodsThis was a cross-sectional and observational study; 65 patients with psoriasis and 50 age- and sex- matched control subjects were included. Data about echocardiographic EFT, CIMT, anthropometric measurements and metabolic profile were obtained. ResultsThe EFT and CIMT were significantly increased (7305 vs. 6505mm, P<001; 074011 vs. 060007mm, P<001, respectively) in patients with psoriasis compared with the controls. EFT was significantly correlated with CIMT (r=069, P<001). In a multiple linear regression model in which EFT was independently associated with psoriasis (=045, P<001), age (=033, P=001), CIMT (=050, P<001), body mass index (=025, P=001), high-sensitivity C-reactive protein (=032, P<001) and duration of disease (=034, P=003). ConclusionsWe demonstrated that EFT and CIMT are increased in patients with psoriasis, and that echocardiographic EFT is closely correlated with CIMT in patients with psoriasis. The echocardiographic assessment of EFT may have the potential to be a simple marker of subclinical atherosclerosis and increased cardiovascular risk in patients with psoriasis.en_US
dc.identifier.doi10.1111/bjd.12569
dc.identifier.endpage1086en_US
dc.identifier.issn0007-0963
dc.identifier.issn1365-2133
dc.identifier.issue5en_US
dc.identifier.pmid23909282en_US
dc.identifier.scopus2-s2.0-84887116142en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1081en_US
dc.identifier.urihttps://doi.org/10.1111/bjd.12569
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13450
dc.identifier.volume169en_US
dc.identifier.wosWOS:000326354200018en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofBritish Journal of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntima-Media Thicknessen_US
dc.subjectCoronary-Artery-Diseaseen_US
dc.subjectAdipose-Tissueen_US
dc.subjectMetabolic Syndromeen_US
dc.subjectRisk-Factorsen_US
dc.subjectCardiovascular-Diseaseen_US
dc.subjectDiabetes-Mellitusen_US
dc.subjectInflammationen_US
dc.subjectAssociationen_US
dc.subjectHearten_US
dc.titleIncreased epicardial fat tissue is a marker of subclinical atherosclerosis in patients with psoriasisen_US
dc.typeArticleen_US

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