Left ventricular systolic dysfunction in patients with ankylosing spondylitis without clinically overt cardiovascular disease by speckle tracking echocardiography
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Dosyalar
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Heidelberg
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The aim of this study was to evaluate left ventricular systolic and diastolic function using speckle tracking echocardiography (STE) in order to detect subclinical left ventricular dysfunction in patients with ankylosing spondylitis (AS). Twenty-six AS patients (age 43.7 +/- A 11.8 years, disease duration 11.83 +/- A 10.98 years) and 26 healthy controls, matched for age, sex, body mass index, and smoking, were enrolled in this cross-sectional study. All patients underwent two-dimensional, Doppler, tissue Doppler, and speckle tracking echocardiography. The mitral early/late diastolic inflow velocity ratio (1.0 +/- A 0.4 vs. 1.5 +/- A 0.5; p < 0.001) and the mitral E-wave velocity (8.1 +/- A 2 vs. 11.1 +/- A 3; p < 0.001) were lower in the AS patients than in the controls. The ejection fraction did not differ between the patients and controls (64 +/- A 4.2 vs. 64.8 +/- A 2.3; p = 0.402). All segments showed a significant decrease in left ventricular diastolic and systolic strain values in the patients with AS when compared with the healthy controls (p < 0.001). Despite no clinical evidence of cardiovascular disease, patients with AS may have impaired left ventricular systolic function as assessed by STE.
Açıklama
Anahtar Kelimeler
Ankylosing spondylitis, Left ventricle dysfunction, Strain echocardiography
Kaynak
Rheumatology International
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
35
Sayı
4
