Left ventricular systolic dysfunction in patients with ankylosing spondylitis without clinically overt cardiovascular disease by speckle tracking echocardiography

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dc.contributor.authorUstun, Nilgun
dc.contributor.authorKurt, Mustafa
dc.contributor.authorNacar, Alper Bugra
dc.contributor.authorKarateke, Hacer Paksoy
dc.contributor.authorGuler, Hayal
dc.contributor.authorTurhanoglu, Ayse Dicle
dc.date.accessioned2024-09-18T19:54:24Z
dc.date.available2024-09-18T19:54:24Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate left ventricular systolic and diastolic function using speckle tracking echocardiography (STE) in order to detect subclinical left ventricular dysfunction in patients with ankylosing spondylitis (AS). Twenty-six AS patients (age 43.7 +/- A 11.8 years, disease duration 11.83 +/- A 10.98 years) and 26 healthy controls, matched for age, sex, body mass index, and smoking, were enrolled in this cross-sectional study. All patients underwent two-dimensional, Doppler, tissue Doppler, and speckle tracking echocardiography. The mitral early/late diastolic inflow velocity ratio (1.0 +/- A 0.4 vs. 1.5 +/- A 0.5; p < 0.001) and the mitral E-wave velocity (8.1 +/- A 2 vs. 11.1 +/- A 3; p < 0.001) were lower in the AS patients than in the controls. The ejection fraction did not differ between the patients and controls (64 +/- A 4.2 vs. 64.8 +/- A 2.3; p = 0.402). All segments showed a significant decrease in left ventricular diastolic and systolic strain values in the patients with AS when compared with the healthy controls (p < 0.001). Despite no clinical evidence of cardiovascular disease, patients with AS may have impaired left ventricular systolic function as assessed by STE.en_US
dc.identifier.doi10.1007/s00296-014-3130-z
dc.identifier.endpage611en_US
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.issue4en_US
dc.identifier.pmid25234797en_US
dc.identifier.scopus2-s2.0-84925467240en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage607en_US
dc.identifier.urihttps://doi.org/10.1007/s00296-014-3130-z
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7716
dc.identifier.volume35en_US
dc.identifier.wosWOS:000351586100004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofRheumatology Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing spondylitisen_US
dc.subjectLeft ventricle dysfunctionen_US
dc.subjectStrain echocardiographyen_US
dc.titleLeft ventricular systolic dysfunction in patients with ankylosing spondylitis without clinically overt cardiovascular disease by speckle tracking echocardiographyen_US
dc.typeArticleen_US

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