Intra-day changes in the levels of biochemistry parameters

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dc.authorscopusid6603061715
dc.authorscopusid57219858233
dc.authorscopusid57223045661
dc.authorscopusid57219452370
dc.authorscopusid57210586313
dc.contributor.authorArpaci, Abdullah
dc.contributor.authorDogan, Serdar
dc.contributor.authorGul, Bahar Unlu
dc.contributor.authorKus, Berna
dc.contributor.authorDirican, Emre
dc.date.accessioned2024-09-19T15:45:34Z
dc.date.available2024-09-19T15:45:34Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjectives: People mostly live in the nonfasting state during a normal 24-h cycle. This study aims to compare the levels of 18 biochemical parameters during different hours of the day. Methods: A total of 18 biochemical tests of patients who visited outpatient clinics only once between January 1, 2010, and December 31, 2019, were evaluated at the Hatay Mustafa Kemal University (HMKU) Central Laboratory by using hospital database information. The tests are albumin (Alb), aspartate aminotransaminase (AST), alanine aminotransam-inase (ALT), alkaline phosphatase (ALP), amylase, blood urea nitrogen (BUN), calcium (Ca), total cholesterol (TC), cre-atine kinase (CK), creatinine (Cr), gamma-glutamyltransferase (GGT), glucose, high-density lipoprotein cholesterol (HDL-C), inorganic phosphorus (Pi), iron (Fe), total protein (TP), triglyceride (TG), and lipase. The blood samples of the patient were divided into eight groups according to their collection time as follows: (a) 07:00-07:59, (b) 08:00-08:59, (c) 09:00-09:59, (d) 10:00-10:59, (e) 11:00-11:59, (f) 12:00-13:59, (g) 14:00-14:59, and (h) 15:00-17:00. Results: A statistically significant difference was found between the groups in terms of all parameters except amylase, GGT, and TP (p<0.05). The effect size refers to the minimum amount of difference that is clinically significant. According to the effect size values, there was no significant difference between time groups in the following parameters: Alb, ALT, AST, Pi, Ca, TC, Cr, Fe, glucose, BUN, lipase, TG, ALP, HDL-C, and CK (?<0.30). Conclusion: When considering all of the results, nonfasting screening would not only be acceptable but also make physiologic sense. © 2022, Kare Publishing. All rights reserved.en_US
dc.description.sponsorshipHatay Mustafa Kemal University Hospitalen_US
dc.identifier.doi10.14744/ijmb.2022.54227
dc.identifier.endpage108en_US
dc.identifier.issn2587-2362
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85142513813en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage101en_US
dc.identifier.trdizinid521089en_US
dc.identifier.urihttps://doi.org/10.14744/ijmb.2022.54227
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/521089
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14772
dc.identifier.volume5en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherKare Publishingen_US
dc.relation.ispartofInternational Journal of Medical Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectClinical chemistry testsen_US
dc.subjectdatabase management systemen_US
dc.subjectstatistical data analysisen_US
dc.titleIntra-day changes in the levels of biochemistry parametersen_US
dc.typeArticleen_US

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