The effect of Theranekron® in intact and ischemia-reperfusion injured rat ovary

Basit Öğe Kaydı
dc.contributor.authorGüler, Fatma
dc.contributor.authorKozlu, Tolunay
dc.contributor.authorErgün, Yaşar
dc.contributor.authorAlan, Beyza Suvarıklı
dc.contributor.authorTutar, Tolga
dc.date.accessioned2024-09-19T16:25:00Z
dc.date.available2024-09-19T16:25:00Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe effect of Theranekron® on ovaries were evaluated in healthy and ischemia- reperfusion injury rat model. Thirty-eight female, nulligravida Wistar Albino rats were divided into four groups, as follows: group 1: control, group 2: Theranekron®, group 3: ischemia-reperfusion and group 4: ischemia-reperfusion+Theranekron®. Each groups were analyzed biochemically and histologically. As compared with group 1, there was a significant increase in the number of atretic follicles and interstitial cells in group 2. Also, nitrite, nitrate, and malondialdehyde levels increased significantly in group 2. Group 3 represented intense hyperemia and hemorrhages on follicles surrounding the cortex and in the corpus luteum and marked increase in the number of atretic follicles, compared to group 2. Nitrite and nitrate levels in group 3 were similar to those in group 2, but malondialdehyde levels were lower than those in group 2. Group 4 showed very slight decrease in interstitial cells compared with group 2 and group 3. In this group, malondialdehyde levels decreased compared to group 2 and increased compared to control and group 3. Based on the results obtained, we may speculate that Theranekron® may have some degenerative effects on intact ovaries, and may have ameliorating effects on ischemia reperfusion injury in ovaries.en_US
dc.identifier.doi10.35864/evmd.1230741
dc.identifier.endpage29en_US
dc.identifier.issn1016-3573
dc.identifier.issue1en_US
dc.identifier.startpage23en_US
dc.identifier.trdizinid1183892en_US
dc.identifier.urihttps://doi.org/10.35864/evmd.1230741
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1183892
dc.identifier.urihttps://hdl.handle.net/20.500.12483/16122
dc.identifier.volume34en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofEtlik Veteriner Mikrobiyoloji Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIschemia-reperfusionen_US
dc.subjectMalondialdehydeen_US
dc.subjectNitrate/Nitriteen_US
dc.subjectRaten_US
dc.subjectTheranekron®en_US
dc.titleThe effect of Theranekron® in intact and ischemia-reperfusion injured rat ovaryen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
16122.pdf
Boyut:
2.35 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu