Investigation of neutrophil lymphocyte ratio and blood glucose regulation in patients with type 2 diabetes mellitus

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Küçük Resim

Tarih

2014

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Sage Publications Ltd

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objective Leukocytosis is thought to be directly associated with the pathogenesis of atherosclerosis and metabolic syndrome. Increased white blood cell (WBC) count is related to cardiovascular disease in patients with type 2 diabetes mellitus; raised neutrophil lymphocyte ratio (NLR) is associated with metabolic syndrome. There is little information, however, concerning a correlation between glycosylated haemoglobin (HbA(1c)) and NLR. The aim of the present study was to investigate the relationship between NLR and blood glucose regulation. Methods This retrospective study was conducted in patients with type 2 diabetes mellitus, divided into two groups according to HbA(1c) levels: group 1, HbA(1c) levels7%; group 2, HbA(1c) levels>7%. Venous WBC, neutrophil and lymphocyte counts were determined. Results Of 71 patients included, fasting serum glucose, neutrophil and WBC counts were significantly higher in group 2 compared with group 1. NLR had a positive correlation with HbA(1c). Conclusion There may be a significant relationship between NLR and blood glucose regulation. The authors propose that increased NLR may be associated with elevated HbA(1c) in patients with type 2 diabetes mellitus.

Açıklama

Anahtar Kelimeler

Glycosylated haemoglobin (HbA(1c)), neutrophil lymphocyte ratio, diabetes mellitus

Kaynak

Journal of International Medical Research

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

42

Sayı

2

Künye