Investigation of neutrophil lymphocyte ratio and blood glucose regulation in patients with type 2 diabetes mellitus

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dc.authoridSefil, Fatih/0000-0001-5534-7448
dc.authoridUstun, Ihsan/0000-0002-5848-1586
dc.authoridDokuyucu, Recep/0000-0001-6837-3477
dc.authoridUlutas, Kemal Turker/0000-0003-2852-0449
dc.authoridDokuyucu, Recep/0000-0001-7881-8871
dc.authoridSumbul, Ahmet Taner/0000-0002-5573-906X
dc.contributor.authorSefil, Fatih
dc.contributor.authorUlutas, Kemal Turker
dc.contributor.authorDokuyucu, Recep
dc.contributor.authorSumbul, Ahmet Taner
dc.contributor.authorYengil, Erhan
dc.contributor.authorYagiz, Abdullah Erman
dc.contributor.authorYula, Erkan
dc.date.accessioned2024-09-18T20:25:25Z
dc.date.available2024-09-18T20:25:25Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective Leukocytosis is thought to be directly associated with the pathogenesis of atherosclerosis and metabolic syndrome. Increased white blood cell (WBC) count is related to cardiovascular disease in patients with type 2 diabetes mellitus; raised neutrophil lymphocyte ratio (NLR) is associated with metabolic syndrome. There is little information, however, concerning a correlation between glycosylated haemoglobin (HbA(1c)) and NLR. The aim of the present study was to investigate the relationship between NLR and blood glucose regulation. Methods This retrospective study was conducted in patients with type 2 diabetes mellitus, divided into two groups according to HbA(1c) levels: group 1, HbA(1c) levels7%; group 2, HbA(1c) levels>7%. Venous WBC, neutrophil and lymphocyte counts were determined. Results Of 71 patients included, fasting serum glucose, neutrophil and WBC counts were significantly higher in group 2 compared with group 1. NLR had a positive correlation with HbA(1c). Conclusion There may be a significant relationship between NLR and blood glucose regulation. The authors propose that increased NLR may be associated with elevated HbA(1c) in patients with type 2 diabetes mellitus.en_US
dc.identifier.doi10.1177/0300060513516944
dc.identifier.endpage588en_US
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue2en_US
dc.identifier.pmid24567354en_US
dc.identifier.scopus2-s2.0-84898687129en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage581en_US
dc.identifier.urihttps://doi.org/10.1177/0300060513516944
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10297
dc.identifier.volume42en_US
dc.identifier.wosWOS:000333007000034en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal of International Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGlycosylated haemoglobin (HbA(1c))en_US
dc.subjectneutrophil lymphocyte ratioen_US
dc.subjectdiabetes mellitusen_US
dc.titleInvestigation of neutrophil lymphocyte ratio and blood glucose regulation in patients with type 2 diabetes mellitusen_US
dc.typeArticleen_US

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