Effects of Bovine Amniotic Fluid on Acute Corneal Alkali Burns in the Rat

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dc.authoridGonenci, Ramazan/0000-0002-4043-2612
dc.contributor.authorGonenci, Ramazan
dc.contributor.authorAltug, Muhammed Enes
dc.contributor.authorKoc, Ahmet
dc.contributor.authorYalcin, Alper
dc.date.accessioned2024-09-18T19:52:35Z
dc.date.available2024-09-18T19:52:35Z
dc.date.issued2009
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBovine Amniotic Fluid (BAF) was topically applied for treatment group, whereas isotonic saline solution was applied for saline group in the study after an alkali burn was created in the right eye of 16 rats with 2.5 N NaOH. Density and area of the corneal opacity, area of the corneal epithelial defect, corneal neovascularization and complications were clinically evaluated and scored using a modified model at post-injury days 0, 3, 7 and 14. At the end of the experiment, all the eyes were histologically examined after enucleation. It was resultantly found that BAF has slightly decreased corneal opacification, increased reepithelization and limited neovascularization, hyphema and total corneal erosions. But these clinical ocular damage scores were not statistically significant. In histological examination, the number of polymorphonuclear leucocytes, corneal thicknesses, edema, keratinization, vascularization and inflammation were significantly reduced by BAF compared to the saline group. Based on these positive effects in severe burns, it was concluded that BAF could be a new topical alternative agent for veterinary ophthalmology thereafter.en_US
dc.identifier.endpage623en_US
dc.identifier.issn1680-5593
dc.identifier.issn1993-601X
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-67650624424en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage617en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7531
dc.identifier.volume8en_US
dc.identifier.wosWOS:000265888900003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMedwell Onlineen_US
dc.relation.ispartofJournal of Animal and Veterinary Advancesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlkali burnen_US
dc.subjectBAFen_US
dc.subjectbovine amniotic fluiden_US
dc.subjectcorneaen_US
dc.subjectraten_US
dc.titleEffects of Bovine Amniotic Fluid on Acute Corneal Alkali Burns in the Raten_US
dc.typeArticleen_US

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