Poor myocardial blush grade accompanies to higher sudden death risk scores of hypertrophic cardiomyopathy

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dc.authorid0000-0001-7988-7027en_US
dc.authorid0000-0003-2041-8335en_US
dc.contributor.authorAkkuş, Oğuz
dc.contributor.authorKaplan, Mehmet
dc.contributor.authorDuman, Fatma
dc.contributor.authorYalçın, Fatih
dc.date.accessioned2020-07-23T11:02:48Z
dc.date.available2020-07-23T11:02:48Z
dc.date.issued2019en_US
dc.departmentTayfur Ata Sökmen Tıp Fakültesien_US
dc.description.abstractAim: Hypertrophic cardiomyopathy (HCM) is predominantly inherited as an autosomal dominant disease. The aim of our study was to evaluate angiographic microvascular flow and predictors of poor MBG in patients with HCM. Material and Methods: Patients with poor MBG (MBG 0/1, n=43), and patients with normal MBG (MBG 2/3, n=15) were included retrospectively. Results: Family history and left ventricular end-diastolic diameter were significantly higher in the poor MBG group (p = 0.025, p=0.021). Left atrium diameter and moderate to severe mitral regurgitation (MR) were significantly higher in the normal MBG group (p=0.034, p=0.002). Percentage of SCD risk was significantly higher in patients with poor MBG (p=0.014). Moderate and severe mitral regurgitation (odds ratio =0.013, p=0.004) and HCM-SCD risk score (odds ratio = 0,398, p=0.009) were found to be independent parameters for predicting poor myocardial blush grade. The cut-off value of HCM-SCD risk score obtained by ROC curve analysis was 3.10 for the prediction of poor myocardial blush grade (sensitivity: 76.2%, specificity: 76.7%). The area under the curve (AUC) was 0.712 (p=0.016). Conclusions: Our study results demonstrated the increased risk of sudden cardiac death accompanies poor myocardial blush grade in patients with HCM. If confirmed by further studies, poor MBG may convey SCD-HCM risk of higher rates.en_US
dc.identifier.citationAkkus, O., Kaplan, M., Duman, F., & Yalcin, F. (2019). Poor myocardial blush grade accompanies to higher sudden death risk scores of hypertrophic cardiomyopathy. Annals of Medical Research, 26(9), 2032-8.en_US
dc.identifier.doi10.5455/annalsmedres.2019.03.165en_US
dc.identifier.endpage2038en_US
dc.identifier.issn2636-7688
dc.identifier.issue9en_US
dc.identifier.startpage2032en_US
dc.identifier.trdizinid318592en_US
dc.identifier.urihttps://dx.doi.org/10.5455/annalsmedres.2019.03.165
dc.identifier.urihttps://hdl.handle.net/20.500.12483/2923
dc.identifier.volume26en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherİnönü Üniversitesien_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/
dc.subjectHypertrophic cardiomyopathyen_US
dc.subjectMicrovascular diseaseen_US
dc.subjectSudden cardiac death risk scoreen_US
dc.titlePoor myocardial blush grade accompanies to higher sudden death risk scores of hypertrophic cardiomyopathyen_US
dc.typeArticleen_US

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