Neoadjuvan kemoterapi uygulanan meme kanserli hastalarda prediktif faktörlerin yeri
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Dosyalar
Tarih
2014
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Yayıncı
Hatay Mustafa Kemal Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Meme kanseri, kadınlarda en sık görülen kanserlerden biridir. Kanserden ölüm nedenleri arasında akciğer kanserinden sonra ikinci sırayı almaktadır. Neoadjuvan kemoterapi, lokal ileri evre meme kanserli hastalara cerrahi operasyondan önce kemoterapi verilmesidir. Böylece, tedavi sonrasında tümör çapı küçültülerek hastaya radikal mastektomi yerine meme koruyucu cerrahi tercih edilebilir. Neoadjuvan tedaviden fayda görebilecek hastaları öngörebilmemizi kolaylaştırabilecek prediktif faktörler bulunmaktadır. Bu tez çalışmasında neoadjuvan kemoterapinin etkileri çeşitli parametrelerle mastektomi materyallerinde değerlendirilmiştir.
Breast cancer is the most common cancer in women and after lung cancer it is the second leading cause of death from cancer. Neoadjuvan chemotherapy is the administration of chemotherapy before surgery to locally advanced breast cancer patients. Thus, the tumor size was reduced after treatment, breast-conserving surgery can be prefered instead of radical mastectomy to the patients. There are predictive factors that facilitate to predict the patients who may benefit from neoadjuvant therapy. In this thesis study, the effects of neoadjuvant chemotherapy was assessed on mastectomy materials with various parameters.
Breast cancer is the most common cancer in women and after lung cancer it is the second leading cause of death from cancer. Neoadjuvan chemotherapy is the administration of chemotherapy before surgery to locally advanced breast cancer patients. Thus, the tumor size was reduced after treatment, breast-conserving surgery can be prefered instead of radical mastectomy to the patients. There are predictive factors that facilitate to predict the patients who may benefit from neoadjuvant therapy. In this thesis study, the effects of neoadjuvant chemotherapy was assessed on mastectomy materials with various parameters.
Açıklama
Anahtar Kelimeler
Patoloji, Pathology