Increased Mean Platelet Volume in Patients with Depression
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Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Derman Medical Publ
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Aim: It is well known that the mean platelet volume (MPV) is a good indicator of platelet activity and the incidence of cardiovascular diseases. Major depressive disorder may emerge in association with the cardiovascular diseases. In this study, we aimed to investigate the relationship between MPV and major depressive disorder. Material and Method: MPV values of 65 patients with major depression were compared with 66 age-and sex-matched healthy subjects. Body mass index (BMI), MPV, platelet count (PLC) of all participants were measured. Beck Depression Scale (BDS) was performed to measure severity of depression. Results: MPV values of patients who had major depression were found to be significantly higher than the control group. Comparing Major Depression with the control group, there was no significant difference in terms of platelet count. In the depression group, there was no correlation between the severity of depression and MPV. Discussion: As a result, the mean platelet volume was determined to have a significant increase in major depressive disorder compared with healthy individuals. This also may be informative about the association between pathologies related vascular structure such as vascular atherosclerosis and depression.
Description
Keywords
Major Depression, Mean Platelet Volume, Platelet Count
Journal or Series
Journal of Clinical and Analytical Medicine
WoS Q Value
N/A
Scopus Q Value
Volume
6
