Increased Mean Platelet Volume in Patients with Depression

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dc.contributor.authorKokacya, Mehmet Hanifi
dc.contributor.authorCopoglu, Umit Sertan
dc.contributor.authorAri, Mustafa
dc.contributor.authorSahpolat, Musa
dc.contributor.authorUlutas, Kemal Turker
dc.contributor.authorKivrak, Yuksel
dc.date.accessioned2024-09-18T20:29:41Z
dc.date.available2024-09-18T20:29:41Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim: It is well known that the mean platelet volume (MPV) is a good indicator of platelet activity and the incidence of cardiovascular diseases. Major depressive disorder may emerge in association with the cardiovascular diseases. In this study, we aimed to investigate the relationship between MPV and major depressive disorder. Material and Method: MPV values of 65 patients with major depression were compared with 66 age-and sex-matched healthy subjects. Body mass index (BMI), MPV, platelet count (PLC) of all participants were measured. Beck Depression Scale (BDS) was performed to measure severity of depression. Results: MPV values of patients who had major depression were found to be significantly higher than the control group. Comparing Major Depression with the control group, there was no significant difference in terms of platelet count. In the depression group, there was no correlation between the severity of depression and MPV. Discussion: As a result, the mean platelet volume was determined to have a significant increase in major depressive disorder compared with healthy individuals. This also may be informative about the association between pathologies related vascular structure such as vascular atherosclerosis and depression.en_US
dc.identifier.doi10.4328/JCAM.2590
dc.identifier.endpage15en_US
dc.identifier.issn1309-0720
dc.identifier.issn1309-2014
dc.identifier.startpage13en_US
dc.identifier.urihttps://doi.org/10.4328/JCAM.2590
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11011
dc.identifier.volume6en_US
dc.identifier.wosWOS:000215585400017en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherDerman Medical Publen_US
dc.relation.ispartofJournal of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMajor Depressionen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectPlatelet Counten_US
dc.titleIncreased Mean Platelet Volume in Patients with Depressionen_US
dc.typeArticleen_US

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