EFFECT OF GM-CSF LEVELS ON OSTEOPOROSIS IN POSTMENOPAUSAL PERIOD

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dc.authoridKoca, Irfan/0000-0003-1257-6843
dc.authoridDokuyucu, Recep/0000-0001-6837-3477
dc.authoridSumbul, Ahmet Taner/0000-0002-5573-906X
dc.contributor.authorYagiz, Abdullah Erman
dc.contributor.authorDokuyucu, Recep
dc.contributor.authorSumbul, Ahmet Taner
dc.contributor.authorYengil, Erhan
dc.contributor.authorUstun, Nilgul
dc.contributor.authorKoca, Irfan
dc.contributor.authorGogebakan, Bulent
dc.date.accessioned2024-09-18T20:52:59Z
dc.date.available2024-09-18T20:52:59Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractObjectives: Cytokines and hematopoietic growth factors may play a role in the pathogenesis of osteoporosis. The aim of this study was to assess the relationship between osteoporosis (OP) and granulocyte-macrophage colony stimulating factor (GM-CSF) in postmenopausal period. Materials and methods: Total number of 80 female patients between the ages of 45-75 and who had entered in menopause from at least one year and diagnosed with OP were enrolled in this study. As a control group, 80 healthy volunteer female patients who had entered in menopause from at least one year and had no diagnosis of OP were selected. The age, height, weight, body mass index, duration of menopause, exercise habits of the patients and controls were recorded and bone mineral density was measured for the diagnosis of OP. The serum GM-CSF concentrations of individuals were quantified using a specific enzyme immunoassay kit. Results: There was no significant relationship between the mean age, duration of menopause and body mass index of patients and controls (p>0.05). Serum GM-CSF levels of patients and control groups did not differ significantly (p> 0.05). Conclusion: The results of our study showed that there was no significant correlation between osteoporosis and serum GMCSF levels. Osteoporosis might be correlating with the levels of GM-CSF in bone microenvironment rather than serum levels.en_US
dc.identifier.endpage200en_US
dc.identifier.issn0393-6384
dc.identifier.issue1en_US
dc.identifier.startpage197en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11524
dc.identifier.volume30en_US
dc.identifier.wosWOS:000335937700031en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOsteoporosisen_US
dc.subjectgranulocyte-macrophage colony stimulating factoren_US
dc.subjectmenopauseen_US
dc.titleEFFECT OF GM-CSF LEVELS ON OSTEOPOROSIS IN POSTMENOPAUSAL PERIODen_US
dc.typeArticleen_US

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