Widespread maculopapular rash due to intramuscular interferon beta-1a during the treatment of multiple sclerosis
Yükleniyor...
Dosyalar
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sage Publications Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
We describe a 41- year- old woman with multiple sclerosis, who presented erythematous maculopapular rash on the trunk and extremities after the second injection of interferon beta- 1a. Histopathologic examination of the lesion revealed lymphocytic exocytosis and perivascular lymphocytic infiltrate in the dermis. Oral antihistamine and topical corticosteroid was started. After improvement of the lesions, the third injection was performed. However, the same reaction occurred. A prick test, which was performed 6 weeks after the eruption, also revealed positive reaction. Although injection- site reactions have been observed with interferon beta- 1a, to our knowledge there have been no previous reports of interferon beta- 1a- induced widespread cutaneous reaction.
Açıklama
Anahtar Kelimeler
adverse reaction, cutaneous, interferon beta-1a, maculopapular rash, multiple sclerosis
Kaynak
Multiple Sclerosis
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
14
Sayı
2
