Widespread maculopapular rash due to intramuscular interferon beta-1a during the treatment of multiple sclerosis

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dc.authoridDUMAN, Taskin/0000-0002-6552-4193
dc.contributor.authorSerarslan, G.
dc.contributor.authorOkuyucu, Ee
dc.contributor.authorMelek, Im
dc.contributor.authorHakverdi, S.
dc.contributor.authorDuman, T.
dc.date.accessioned2024-09-18T19:50:25Z
dc.date.available2024-09-18T19:50:25Z
dc.date.issued2008
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractWe describe a 41- year- old woman with multiple sclerosis, who presented erythematous maculopapular rash on the trunk and extremities after the second injection of interferon beta- 1a. Histopathologic examination of the lesion revealed lymphocytic exocytosis and perivascular lymphocytic infiltrate in the dermis. Oral antihistamine and topical corticosteroid was started. After improvement of the lesions, the third injection was performed. However, the same reaction occurred. A prick test, which was performed 6 weeks after the eruption, also revealed positive reaction. Although injection- site reactions have been observed with interferon beta- 1a, to our knowledge there have been no previous reports of interferon beta- 1a- induced widespread cutaneous reaction.en_US
dc.identifier.doi10.1177/1352458507079945
dc.identifier.endpage261en_US
dc.identifier.issn1352-4585
dc.identifier.issue2en_US
dc.identifier.pmid18337427en_US
dc.identifier.scopus2-s2.0-43149093805en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage259en_US
dc.identifier.urihttps://doi.org/10.1177/1352458507079945
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7428
dc.identifier.volume14en_US
dc.identifier.wosWOS:000254216600018en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofMultiple Sclerosisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectadverse reactionen_US
dc.subjectcutaneousen_US
dc.subjectinterferon beta-1aen_US
dc.subjectmaculopapular rashen_US
dc.subjectmultiple sclerosisen_US
dc.titleWidespread maculopapular rash due to intramuscular interferon beta-1a during the treatment of multiple sclerosisen_US
dc.typeArticleen_US

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