Tip 2 diyabetli hastalarda elektrolit bozuklukları
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Tarih
2017
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
AMAÇ: Tip 2 diyabetli hastalardaki elektrolit değişikliklerini ve bunların glisemi regülasyonu ile ilişkisini değerlendirmektir. GEREÇ ve YÖNTEMLER: Çalışmada, 01.02.2015-30.12.2015 tarihleri arasında hastanemiz Endokrinoloji ve Metabolizma polikliniği ve Nefroloji polikliniklerine değişik nedenlerle başvuran 30- 90 yaş arası diyabet tanısı olan hastaların kayıtları değerlendirildi. Tip 1 Diabetes Mellitus, diüretik, renin anjiotensin aldosteron sistemi blokeri veya bunların kombinasyonunu alanlar, diyare ve kusması olanlar, ciddi kalp yetmezliği, karaciğer sirozu, aktif malignitesi olanlar, tahmini glomerüler filtrasyon hızı <= 60 mL/dk 1.73 m2 olanlar, kalsiyum, magnezyum, D vitamini replasmanı alanlar ve aktif diyabetik ketoasidoz tanısı olanlar değerlendirme dışında bırakıldı. BULGULAR: Çalışmaya alınma ve dışlama kriterleri sonucunda 161' i kadın, 162'si erkek olmak üzere toplam 323 tip 2 diyabetik hasta alındı. Çalışma grubunda en sık gözlenen elektrolit bozukluğu hipomagnezemi idi (%20,2). Serum glukoz düzeyleri ve serum sodyum düzeyleri arasında negatif korelasyon saptandı (p<0,05; r=-0,28). Glukoz ile diğer elektrolitler (potasyum, kalsiyum, fosfor ve magnezyum) arasında herhangi bir korelasyon tespit edilmedi. SONUÇ: Tip 2 diyabet gerek hastalığın fizyopatolojisi gerekse kullanılan ilaçlar ve komorbit durumlar nedeniyle elektrolit bozukluklarının sık görüldüğü bir durumdur. Bu hastaların takibinde elektrolitlerin değerlendirilmesi ve herhangi bir bozukluk tespit edildiğinde bu durumu düzeltmeye yönelik önlemler alınması mortalite ve morbiditenin azaltılması açısından önemlidir.
OBJECTIVE: The aim of the was is to evaluate electrolyte changes and the relationship between electrolytes and glucose regulation in type 2 diabetic patients. MATERIAL and METHODS: Data of diabetic patients aged 30-90 years who came to the Endocrinology and Metabolism and the Nephrology outpatient clinics between 01.02.2015 and 30.12.2015 for any reason were reviewed. Patients with type 1 diabetes mellitus, using diuretics, renin-angiotensin-aldosterone system blockers or combination of these drugs, or calcium, magnesium, vitamin D supplementation, patients with vomiting and diarrhea, serious heart failure, cirrhosis, active malignancy, estimated glomerular filtration rate <=60 mL/min 1.73 m2 , and those diagnosed with diabetic ketoacidosis are excluded from the study. RESULTS: According to the inclusion and exclusion criteria, 323 type 2 diabetic patients consisting of 161 women and 162 men were evaluated. Hypomagnesemia was the major electrolyte problem in our study group with a prevalence of 20.2%. A negative correlation was observed between serum glucose and sodium (p<0.05; r=-0.28). There was no correlation between glucose and other electrolytes (potassium, calcium, phosphorus and magnesium). CONCLUSION: Electrolyte imbalances are frequently seen in diabetic patients because of physiopathologic changes and therapeutic drugs as well as comorbidities. Evaluation of electrolytes during the follow up period of these patients, and in the case of any electrolyte abnormalities their appropriate management is important for decreasing both mortality and morbidity.
OBJECTIVE: The aim of the was is to evaluate electrolyte changes and the relationship between electrolytes and glucose regulation in type 2 diabetic patients. MATERIAL and METHODS: Data of diabetic patients aged 30-90 years who came to the Endocrinology and Metabolism and the Nephrology outpatient clinics between 01.02.2015 and 30.12.2015 for any reason were reviewed. Patients with type 1 diabetes mellitus, using diuretics, renin-angiotensin-aldosterone system blockers or combination of these drugs, or calcium, magnesium, vitamin D supplementation, patients with vomiting and diarrhea, serious heart failure, cirrhosis, active malignancy, estimated glomerular filtration rate <=60 mL/min 1.73 m2 , and those diagnosed with diabetic ketoacidosis are excluded from the study. RESULTS: According to the inclusion and exclusion criteria, 323 type 2 diabetic patients consisting of 161 women and 162 men were evaluated. Hypomagnesemia was the major electrolyte problem in our study group with a prevalence of 20.2%. A negative correlation was observed between serum glucose and sodium (p<0.05; r=-0.28). There was no correlation between glucose and other electrolytes (potassium, calcium, phosphorus and magnesium). CONCLUSION: Electrolyte imbalances are frequently seen in diabetic patients because of physiopathologic changes and therapeutic drugs as well as comorbidities. Evaluation of electrolytes during the follow up period of these patients, and in the case of any electrolyte abnormalities their appropriate management is important for decreasing both mortality and morbidity.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Türk Nefroloji Diyaliz ve Transplantasyon Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
26
Sayı
3
