Spectral classical least square calibration approach for the simultaneous determination and stability test of Sulphadiazme and Trimethoprim in bolus

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dc.authorscopusid25654919100
dc.authorscopusid36160948700
dc.authorscopusid36160870600
dc.contributor.authorEge, Hismiogullari Şahver
dc.contributor.authorEnder, Yarsan
dc.contributor.authorErdal, Dinc
dc.date.accessioned2024-09-19T15:45:29Z
dc.date.available2024-09-19T15:45:29Z
dc.date.issued2010
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractA simple spectral classical least square calibration approach were proposed for the simultaneous quantitative evaluation and stability testing of sulphadiazine and trunethoprun in an animal commercial preparation, bolus without requiring a priory separation step. Stability tests of sulphadiazine and trimethoprim in bolus were performed by using the following conditions: Room temperature, refrigerator and etuve (37oC) for each 3 month during 12 months. A spectral classical least square calibration based on the use of absorptivities at three-wavelength set (241, 257 and 288 run) was computed by using the linear concentration range of 4.0-22.0 ug mL-1 for sulphadiazine and 3.0-18.0 jug mL-1 for trimethoprim. The proposed spectral least square calibration was validated by using various synthetic binary mixtures containing the above veterinary drugs. Simultaneous analysis and stability test of sulphadiazine and trunethoprun in commercial veterinary bolus was established by the spectral classical calibration method. © Medwell Journals, 2010.en_US
dc.identifier.doi10.3923/javaa.2010.857.861
dc.identifier.endpage861en_US
dc.identifier.issn1993-601X
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-77953731155en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage857en_US
dc.identifier.urihttps://doi.org/10.3923/javaa.2010.857.861
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14722
dc.identifier.volume9en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Animal and Veterinary Advancesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChemometryen_US
dc.subjectSimultaneous determinationen_US
dc.subjectSpectral classical least squareen_US
dc.subjectStability testen_US
dc.subjectSulphadiazineen_US
dc.subjectTrimethoprimen_US
dc.titleSpectral classical least square calibration approach for the simultaneous determination and stability test of Sulphadiazme and Trimethoprim in bolusen_US
dc.typeArticleen_US

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