The effect of initial complaints and third year MRI lesion load on EDSS of multiple sclerosis patients

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dc.contributor.authorGüntel, Murat
dc.contributor.authorDuman, Taşkın
dc.contributor.authorDemetgül, Özcan
dc.date.accessioned2024-09-19T16:26:48Z
dc.date.available2024-09-19T16:26:48Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim: We aimed to investigate the effect of initial complaints and third-year MRI lesion burden on Expanded Disability Status Scale (EDSS) of Multiple Sclerosis Patients.Materials and Methods: Patients who were admitted to the Mustafa Kemal University Faculty of Medicine Neurology clinic and diagnosed with Multiple Sclerosis according to Mc Donald diagnostic criteria were included in the study. The initial symptoms of patients, MRI lesion burden at the end of the third year, and the EDSS score were recorded retrospectively from the patient files. 74.5 % of the participants were female and 25.5 % were male. The most common initial symptoms were: Sensory symptoms, vision symptoms, pyramidal tract symptoms, and polysymptomatic. The mean age of the patients was 33.4. Mean EDSS was found to be 1.8±1.3. The total number of lesions in the brain was 14.8 ± 4.83 on average.Results: If patients compared according to the initial symptoms at the end of the third year, the highest EDSS score was at the polysymptomatic onset group, the second-highest score was at the motor onset group. The patients with the initial symptoms of motor or polysymptomatic group had a higher mean EDSS score than the patients with the initial symptoms of vision, sensorial symptoms, or cranial neuropathy. When we examine the relationship between MRI lesion load at the end of the third year and the EDSS score, there is a strong positive correlation between them. Patients who have more lesions in the brain on MRI studies have higher average EDSS scores than patients who have fewer lesions in the brain.Conclusion: We found that the initial symptoms are directly related to the third-year EDSS score and the prognosis of the disease. We found that there was a significant relationship between the number of lesions in the brain on MRI studies at the end of the third year and the mean EDSS score.en_US
dc.identifier.doi10.5455/annalsmedres.2020.04.316
dc.identifier.endpage433en_US
dc.identifier.issn2636-7688
dc.identifier.issue2en_US
dc.identifier.startpage429en_US
dc.identifier.trdizinid429274en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2020.04.316
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/429274
dc.identifier.urihttps://hdl.handle.net/20.500.12483/16357
dc.identifier.volume28en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe effect of initial complaints and third year MRI lesion load on EDSS of multiple sclerosis patientsen_US
dc.typeArticleen_US

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