Evaluation of the effectiveness of using two different probiotics in helicobacter eradication treatment

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dc.contributor.authorKoca, Bülent
dc.contributor.authorKılıç, Erol
dc.contributor.authorYürüker, Saım Savas
dc.contributor.authorYıldırım, Murat
dc.contributor.authorBostan, Mustafa Sami
dc.contributor.authorUğurlu, Celil
dc.contributor.authorÖzkan, Namık
dc.date.accessioned2024-09-19T16:21:01Z
dc.date.available2024-09-19T16:21:01Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIntroduction: We aimed to evaluate the effects of the addition of probiotics containing Lactobacillus acidophilus\r+ Bifidobacterium animalis Subsp lactis to the classic triple treatment protocol (lansoprozole +\ramoxycillin + clarithromycin) on the success of Helicobacter pylori eradication and antibiotic side effects.\rMaterials and Methods: Standard therapy (lansoprozole + amoxycillin + clarithromycin), and probiotics containing\rin addition to standard therapy were determined. Patients in both groups were treated for 14 days.\rThe prebiotic, containing two different strains, was in capsule form and used twice a day. We demonstrated\rthe helicobacter eradication status by looking at the helicobacter antigen from the stool. Statistical analyzes\rbetween the two groups were made using the pearson Chi-square test. P<0.05 was accepted as the\rsignificance level.\rResults: The rate of discontinuing treatment due to side effects was 15.3% in group 1, this rate was 4.5% in\rgroup 2. When double probiotics were added to the treatment, it was observed that there was a decrease\rof 11.2% in serious side effects (p<0.001). After the completion of the treatments. It was observed that\rhelicobacter eradication was achieved in 152 out of 222 patients (68%) in group 1 and in 214 (89%) of 240\rpatients in group 2. When double probiotics were added to the treatment, it was observed that the success\rof eradication increased by 21% (p<0.001).\rConclusion: Combined use of probiotic increases helicobacter eradication in addition to reducing the side\reffects of antibiotics due to H. pylori.en_US
dc.identifier.doi10.14744/less.2021.03764
dc.identifier.endpage181en_US
dc.identifier.issn2587-0610
dc.identifier.issue4en_US
dc.identifier.startpage176en_US
dc.identifier.trdizinid519227en_US
dc.identifier.urihttps://doi.org/10.14744/less.2021.03764
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/519227
dc.identifier.urihttps://hdl.handle.net/20.500.12483/15529
dc.identifier.volume28en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofLaparoscopic Endoscopic Surgical Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of the effectiveness of using two different probiotics in helicobacter eradication treatmenten_US
dc.typeArticleen_US

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