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Öğe Antibiotic use in acute respiratory infections in health care providers and their family members(Turkiye Klinikleri, 2006) Önlen, Yusuf; Özer, Cahit; Ako?lu, Ertap; Sangün, Özlem; Özer, Burçin; Savaş, Lütfü; Incecik, FarukObjective: The aim of this study was to evaluate the diagnoses and treatment of respiratory infections in health care providers and their family members, and also to investigate the antibiotic types and prescription rates according to specialty and institute of the attending physician. Metarial and Methods: All doctor visits of health care providers and their family members at Antakya City center, in Primary Health Care Centers, State Hospital and Mustafa Kemal University School of Medicine, between November 2004 and May 2005 were retrospectively evaluated. Cases of upper respiratory tract infections, acute tonsillitis, acute pharyngitis, acute sinusitis, acute otitis media, acute bronchitis, tracheobronchitis and bronchiolitis were included in the study while pneumoniae and inpatient treatments were excluded. Specialty and institution of the attending physician, medications used and diagnoses of patients were determined. Results: Of the 1145 patients, 611 (53.4%) were females and 534 (46.6%) were males, with a mean age of 19.33 ± 15.44 years (range: 1-66 years). Antibiotic use did not differ according to gender (p= 0.208) and age (p= 0.276). The most frequent diagnoses were upper respiratory tract infections (70.3%), acute tonsillopharyngitis (12.5%), acute bronchitis (8.5%), acute sinusitis (5.5%) and acute otitis media (3.0%). Overall antibiotic prescription rate was 88.0% and the most frequently prescribed antibiotics were amoxicilline-clavulonate (36,9%), second generation cephalosporins (10.3%) and macrolides (8.6%). There was no significant statistical difference between the health care steps or the institution (p= 0.283) and specialties of physicians (p= 0.193) according to the antibiotic prescription rate. Conclusion: We found that antibiotics were frequently prescribed for acute respiratory tract infections among health care providers and their families; and age and gender of the patient or the institution of the physician had no effect on this issue. Copyright © 2006 by Türkiye Klinikleri.Öğe Causes of headache in childhood(2006) Incecik, Faruk; Sangün, Özlem; Ako?lu, Ertap; Melek, Ismet; Öksüz, Hüseyin; Duman, TaşkinHeadaches in childhood can be the result of serious organic events as well as the benign causes. In this paper, it is aimed to investigate the etiology of the headache complaint in childhood. This research is made retrospectively in 62 cases; 40 females and 22 males, who are 6-14 years old and admitted with the complaint of headache. The age of the beginning of the headache, duration, frequency, character, localization, intensity, accompanying factors, triggering factors, family history, physical and neurological examination, waters graphy, EEG, BBT and MRG datas are recorded. There were tension headache in 14 cases (22.6%), sinusitis in 11 (17.7%), migraine in 9 (14.5%), epilepsy in 6 (9.7%), posttraumatic headache in 5 (8.1%), headache related with eye disorders in 2 cases (6.4%), arachnoid cyst in 2 cases (3.2%), intracranial tumor in 1 case (3.2%) and unclassified headache in 10 cases (16.2%). In this study, the mostly seen causes of headaches in childhood are determined as tension headaches, migraine and sinusitis.Öğe Ceftriaxone-Associated Biliary Sludge and Pseudolithiasis in Children(Lippincott Williams & Wilkins, 2007) Onlen, Yusuf; Gali, Edip; Incecik, Faruk; Deviren, Mehmet; Savas, LutfuDetection of incidence and the risk factors of ceftriaxone (CTX)-associated pseudolithiasis (PL) in children. One hundred fourteen patients (75 boys and 39 girls) who used CTX for the treatment of various infections were admitted to the study. Pseudolithiasis was diagnosed by ultrasonography (USG). Ultrasonography was performed at the beginning, on the 5th and 10th days, and at the end of the treatment. Weekly USG was performed to patients who had PL until the findings improved. It was investigated whether the age, sex, weight, treatment duration, dosage, and the way of administration have effects on PL development. Ceftriaxone was administered intravenously. Fifty-seven patients received oncedaily and 57 patients received twice-daily dosage. Pseudolithiasis was observed in 37 (32.5%) of 114 patients. Age, sex, weight, treatment duration, and dosage had no role in PL development, whereas once-or twice-daily administration was found effective. Once-daily dosage of CTX treatment is recommended because of its lower incidence of PL development. Besides that USG should be performed regarding the risk of PL in children who are treated with CTX, further studies are necessary to determine the risk factors.Öğe Effect of valproic acid usage on serum lipid profile in patients with epileps(2006) Incecik, Faruk; Sangün, Özlem; Melek, Ismet; Duman, TaşkinThe effect of antiepileptic drugs on serum lipid concentrations is well known. We investigate the effect of VPA usage on lipid profile. Serum lipid profiles of 25 epileptic patients followed with the VPA mono treatment and a control group consisting of 25 cases with similar sex ratio and ages were measured. The age and sex ratio of the cases in VPA using group and control group were not significantly different. According to control group it is detected that VPA usage has no effects on lipid profile. In the group of patients on VPA treatment, TK, HDL-C, LDL-C, VLDL-C, TG, TK/HDL and LDL/HDL levels were not affected from age, gender, serum level of VPA and the dose and duration of VPA treatment. Conclusion: Because different results were reported in several reports about the effect of VPA on serum lipid profile, which must be used in long term period for the treatment of epilepsy, no consensus has been made. So that we agreed that serum lipid profile must be regularly measured in patients using VPA.Öğe Effect of valproic acid usage on serum protein and immuneglobulin levels in epileptic patients(Aves, 2007) Incecik, Faruk; Sangun, Oziem; Melek, Ismet; Duman, TaskinPurpose: The aim of this study was to research the possible effect of VPA usage on serum protein and immunoglobulin (Ig) levels in epileptic patients. Material and methods: Twenty-five patients followed up after being diagnosed with epilepsy for a minimum of 6 months and were treated with VPA formed the experimental group. In all cases, serum protein and Ig levels, as well as VPA levels were measured. It has been investigated that in VPA using group whether serum protein and Ig levels affected VPA usage doses, treatment period, and levels in addition to the age and sex distribution. Results: There was no statistically significant difference in total protein, albumin, and Ig levels between VPA treatment and control groups. It was determined that in the epileptic group serum protein, albumin, Ig A, M, and G levels were not affected by the VPA serum levels, dosage or treatment duration or age and gender. Conclusion: While the treatment of VPA on epileptic patients, which requires long term usage, a regular follow up for serum proteins and immunoglobulins should be done and because of different results in different studies we suggest that more extensive studies should be performed for the definite results.Öğe Effects of valproic acid on hearing in epileptic patients(Elsevier Ireland Ltd, 2007) Incecik, Faruk; Akoglu, Ertap; Sanguen, Zlem; Melek, Ismet; Duman, TaskinObjective: Since some case reports about the ototoxicity of valproic acid have been published, probable adverse effects of valproic acid on hearing in the epileptic patients became a subject of interest. We wanted to investigate if ototoxicity occurs in pediatric epileptic patients using VPA for long terms. Methods: Twenty-one epileptic patients who have been using valproic acid at least for 6 months as monotherapy and 21 age-sex matched controls were included in the study. Audiometric tests were performed to all patients between the frequencies of 125 and 16,000 Hz. The effects of dosage, duration of therapy and serum levels of the VPA, on the audiometric results were investigated and the audiometric results were compared between the groups. Results: There was no difference in hearing thresholds of the groups between 125 and 16,000 Hz frequencies. Relation could not be established between the duration of VPA therapy, dosage of the drug, blood level of drug, age and sex of the patients and the auditory signs. Conclusions: Although we could not find any deleterious effect of VPA on hearing thresholds in our patient series, we think it is useful to perform audiometric tests at intervals while VPA is being used for tong periods, considering the presented case reports about sensorineural hearing loss. (c) 2007 Elsevier Ireland Ltd. All rights reserved.Öğe Esxtensive intracerebral hemorrhage due to herpes simplex virus encephalitis(2004) Incecik, Faruk; Elkay, Mürüvet; Hergüner, Özlem; Özcan, Kenan; Erbey, Fatih; Altunbaşak, ŞakirHerpes simplex virus is the most common cause of acute sporadic encephalitis and it results typically. in hemorrhagic necrotizing encephalitis in temporal and interior parts of frontal lobes Besides, some atypical localizations and lesions were also reported. They also manifest wide intracerebral hemorrhagic lesions. In this presentation a six month old female infant was admitted to hospital with complaints of fever, irritability, vomitting, decreased oral intake, lethargy and generalized seizures. Neuroimaging studies have revealed bilateral but more in the right side frontotemporal and parietal wide intracerebral hemorrhagic infarctions. With ELİSA technique, cerebrospinal fluid and serum studies for viral etiology were done. After the results of these studies the patient was diagnosed as herpes simplex virus type 1 encephalitis. The patient with herpes simplex virus encephalitis was presented here because of a rarely seen ntracerebral hemorrhage in this age group.Öğe Hearing loss caused by gentamycin: Case report(2005) Incecik, Faruk; Ako?lu, Ertap; Sangün, Özlem; Önlen, YusufAminoglycosides are effective agents in treatment of Gram-negative bacteria, however they exert serious side effects like neuromuscular blokage, nephrotoxicity and ototoxicity. Factors that affect the ototoxicity risk of gentamycine which is an aminoglycoside are dose of the drug, length of treatment period, genetic predisposition, age, usage of aminoglycosides before and other ototoxic drugs together. We determined sensorineural hearing loss after recurrent gentamycin usage in a patient who is 8 years old and wanted to emphasize that odiogram must be performed in such cases.Öğe Immune thrombocytopenic purpura after recombinant hepatitis B vaccine(Ortadogu Ad Pres & Publ Co, 2007) Incecik, Faruk; Oenlen, Yusuf; Oezcan, KenanRecombinant hepatitis B vaccine, which is used throughout the world, rarely has systemic adverse events like polyradiculoneuritis, demyelination of central nervous system. otoimmune hemolytic anemia and immune thrombocytopenia, as well as local side effects. We diagnosed thrombocytopenic purpura in a 10 months-old case, which developed 3 weeks after the 3(rd) dose of the recombinant hepatitis B vaccine. There was no drug history or prior infection. Clinical and laboratory findings of autoimmune or malignant disorders were negative and the bone marrow aspirate was normal. We presented this case to emphasize that thrombocytopenia may develop after recombinant hepatitis B vaccine and thus Should be taken into consideration.Öğe Immune thrombocytopenic purpura after recombinant hepatitis B vaccine: Case report(Turkiye Klinikleri, 2007) Incecik, Faruk; Önlen, Yusuf; Özcan, KenanRecombinant hepatitis B vaccine, which is used throughout the world, rarely has systemic adverse events like polyradiculoneuritis, demyelination of central nervous system, otoimmune hemolytic anemia and immune thrombocytopenia, as well as local side effects. We diagnosed thrombocytopenic purpura in a 10 months-old case, which developed 3 weeks after the 3rd dose of the recombinant hepatitis B vaccine. There was no drug history or prior infection. Clinical and laboratory findings of autoimmune or malignant disorders were negative and the bone marrow aspirate was normal. We presented this case to emphasize that thrombocytopenia may develop after recombinant hepatitis B vaccine and thus should be taken into consideration. Copyright © 2007 by Tûrkiye Klinikleri.Öğe Insulin Like Growth Factor (IGF)(2004) Özcan, Kenan; Incecik, Faruk; Leblebisatan, GökselInsulin Like Growth Hormone (IGF) is a peptide family, depends on and suplying most of the anabolic and mitogenic effects of growth hormon (GH). Beside its GH dependance of serum consantration, showing its effects in tissues other than skeletal ones, increasing the binding of sulphate to the cartilage, stimulating the DNA synthesis and cell proliferation it has also some other duties. IGF-1 is a sample peptide of 70 aminoacids also celled SM-C. IGF-2 is an acidic peptide composed of 67 aminoacids. In both peptides 45 of the 73 aminoacid position are same and almost % 50 aminoacid of them also same with insulin. Both IGF consists of A and D chains binding with disulphide bindings like insulin. We present this review so as to evaluate the findings of the studies made in recent years about Insulin Like Growth Factor.Öğe Iron intoxication at children(2005) Incecik, Faruk; Sangün, ÖzlemIn iron intoxication, ingestion of more than >60 mg/kg alimantery iron, early onset of the symptoms, hyperglycemia (>150 mg/dl), leukocytosis (>15,000 mm3) and determining iron pills at plain graphies of abdomen are signs for severe toxicity and need for chelation therapy. Decontamination of gastrointestinal system (gastric lavage/whole bowel irrigation), infusion of desferrioxamine (15 mg/kg/h) and aggressive management of shock and multiorgan failure are effective. Shock, coagulopathy, severe metabolic acidosis and acute liver failure are signs of poor prognosis. We wanted to discuss clinical picture, diagnosis and treatment of iron intoxication which is frequent in childhood and sometimes a cause for mortality.Öğe Knowledge, attitude and sources of information regarding aids of high school students in Antakya (Antioch) City(De Gruyter Poland Sp Z O O, 2011) Onlen, Yusuf; Savas, Nazan; Ozer, Cahit; Savas, Lutfu; Incecik, Faruk; Kanatli, AliThe aim of the current study was to investigate the knowledge of senior High school students, sources of their knowledge, and the socio-economical facts acting on their knowledge about AIDS. A cross sectional, descriptive study, included a total of 2838 students (1368 females and 1470 males) from 16 high schools of 4 different types (State, Anatolian, Trade, and Private high schools). A questionnaire composed of 5 different sections was used to analyze the knowledge level separately what kind of disease is AIDS, how AIDS can be transmitted, risk factors for AIDS, ways of protection from AIDS, and the sources of their knowledge about AIDS in sections from 1 to 5 respectively. In the first 4 sections the right answers were graded with a score of 2, wrong answers were graded with a score of 0, and a score of 1was given when the student did not have an idea. The maximum score for the first 4 sections of the questionnaire were 12, 38, 14, and 14 respectively. In the 5(th) section the probable sources of knowledge of AIDS, such as school, friends, family, newspapers, books, and TV, were questioned. The mean score received from the questionnaire were 49.50 +/- 6.50 (minimum: 27, maximum: 69). The mean score for the females was 49.69 +/- 6.46, it was 49.32 +/- 6.66 for the males (p > 0.05). The mean score for the first 4 sections were 8.2 +/- 2.15, 24.7 +/- 4, 16, 9.70 +/- 2.30, and 6.90 +/- 1.79, respectively. Statistically, there was no significant difference observed between the 15-16, 17-18, and 19-20 age groups on knowledge about risk factors for AIDS (p > 0.05). However, there were meaningful differences in what kind of disease is AIDS, how AIDS can be transmitted, and ways of protection from AIDS (p < 0.05). In aspect of type of high school the knowledge levels of students about AIDS obtained from the questionnaire were statistically different. Concerning the total score of the questionnaire, the students from trade schools received the lowest score, while the highest score of risk factors for AIDS. were received by Anatolian high school students. The highest score for what kind of illness is AIDS, how AIDS be can transmitted, and ways of protection from AIDS were received by private high school students. High school students in this region do not have enough knowledge on AIDS. They need education especially on ways of protection and spread of AIDS.Öğe Landau-Kleffner syndrome(2004) Incecik, Faruk; Hergüner, Özlem; Elkay, Mürüvet; Altunbaşak, ŞakirLandau-Kleffner syndrome or acquired epileptic aphasia which is seen in children with normal language and motor development is characterized by acute or progressive loss of ability in receptive and expressive language accompanied by paroxysmal changes in electroencephalography. Even though, different treatment modalities have been tried in Landau-Kleffner syndrome until now, these have not been standardized and it has not been possible to determine the predictive factors regarding treatment outcome. For these reasons, we think that a meta-analysis compiling all the relevant data in the literature is required.Öğe METOCLOPRAMIDE INDUCED ACUTE DYSTONIC REACTION: TWO CASE REPORTS(Marmara Univ, Fac Medicine, 2008) Incecik, Faruk; Onlen, Yusuf; Ozer, Cahit; Ozcan, KenanMetoclopramide is a widely used antiemetic agent in paediatric population with the primary side-effect of extrapyramidal reactions. Incidence is 0.5-1% in children while incidence in young adults and elders is 25%. Patients can be misdiagnosed as meningitis, encephalitis, hypocalcemia, seizure and tetanus. We report two cases, 8-month-and 10-year-old boys referred to our hospital with a presumptive diagnosis of encephalitis and diagnosed as metoclopramide induced acute dystonic reaction, to stress this side-effect of metoclopramide.Öğe Metoclopramide induced acute dystonic reaction: Two case reports(2008) Incecik, Faruk; Önlen, Yusuf; Özer, Cahit; Özcan, KenanMetoclopramide is a widely used antiemetic agent in paediatric population with the primary side-effect of extrapyramidal reactions. Incidence is 0.5-1% in children while incidence in young adults and elders is 25%. Patients can be misdiagnosed as meningitis, encephalitis, hypocalcemia, seizure and tetanus. We report two cases, 8-month-and 10-year-old boys referred to our hospital with a presumptive diagnosis of encephalitis and diagnosed as metoclopramide induced acute dystonic reaction, to stress this side-effect of metoclopramide.Öğe An outbreak of aseptic meningitis in Hatay province, Turkey(Riyadh Armed Forces Hospital, 2008) Onlen, Yusuf; Ozkaya, Etem; Savas, Lutfu; Incecik, Faruk; Akcali, Aylin[Abstract Not Available]Öğe Probable montelukast-induced hepatotoxicity in a pediatric patient: case report(K Faisal Spec Hosp Res Centre, 2008) Incecik, Faruk; Onlen, Yusuf; Sangun, Ozlem; Akoglu, Sabahat[Abstract Not Available]Öğe Probable montelukast-induced hepatotoxicity in a pediatric patient: Case report [3](King Faisal Specialist Hospital and Research Centre, 2007) Incecik, Faruk; Onlen, Yusuf; Sangun, Ozlem; Akoglu, Sabahat[No abstract available]Öğe Pseudotumor cerebri, after the withdrawal of steroid treatment(2005) Incecik, Faruk; Leblebisatan, Göksel; Özcan, Kenan; Erbey, FatihPseudotumor cerebri or benign idiopathic intracranial hypertension is a disease characterized by increased intracranial pressure without any lesion with mass effect or hydrocephaly. In etiology beside several factors, we want to present a case with pseudotumor cerebri after steroid withdrawal because its rarely seen.
