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Öğe Anxiety, depression and quality of life in patients with beta thalassemia major and their caregivers(E-Century Publishing Corp, 2014) Yengil, Erhan; Acipayam, Can; Kokacya, Mehmet Hanifi; Kurhan, Faruk; Oktay, Gonul; Ozer, CahitMental health and health related quality of life is commonly affected in patients with chronic problems and their caregivers. In the present study, it was aimed to assess depression and anxiety in patients with beta thalassemia major (BTM) and in their caregivers; and to evaluate effects of these disorders on quality of life. The study was carried out in a district Hereditary Hemoglobinopathy Center and included 88 patients with BTM and 63 of their caregivers. All subjects were assessed using Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and Short Form-36 (SF-36) by a trained psychiatry resident via face-to-face interview. The BDI scores were 17 or above in 20.5% of the patients with BTM and 28.6% of their caregivers (P = 0.248). Of the patients with BTM, there were mild anxiety symptoms in 19.3%, while moderate and severe anxiety symptoms in 14.8% and 4.5%, respectively. Anxiety levels were similar between the patients with BTM and their caregivers (P = 0.878). It was found that BDI and BAI scores were negatively correlated to scores of physical health and mental health components of SF-36 in patients with BTM and their caregivers. In linear regression analysis, it was seen that depression affected physical and mental health of the patients with BTM and their caregivers regardless from anxiety. BTM leads an increase in the frequency of depression and anxiety in both patients and their caregivers, and affects negatively physical and mental components of quality of life.Öğe Applicability of the Demirjian method for dental assessment of southern Turkish children(Elsevier Sci Ltd, 2014) Celik, Salih; Zeren, Cem; Celikel, Adnan; Yengil, Erhan; Altan, AhmetAge-related legal problems are especially common in underdeveloped parts of Turkey. In terms of civil and criminal law, the ages from 13 years to 18 years are critical in our country. Estimation of age is a very significant in aspect of accordance with laws. The aims of this study were to evaluate the applicability and accuracy of the Demirjian technique for assessing southern Turkish children; to analyze the sexual dimorphism of dental age in the studied groups; and to define the relationship between the dental age and the degree of mineralization in mandibular permanent tooth in southern Turkish children. This study was performed using panoramic radiographs from 932 healthy southern Turkish children, 444 girls and 488 boys aged between 4 and 18 years. Statistical evaluations were performed using SPSS (Statistical Package for Social Sciences) for Windows 13.0 software. The mean difference between dental and chronological age was calculated for each age and sex group. The paired t-test was used to compare all data. The chi-square test was used for between-group comparisons of categorical variables. Continuous variables were tested for normality using the Kolmogorov-Smirnov test. Relationships between continuous variables were examined using Pearson's correlation coefficient. The same observer re-examined 700 teeth three months after the first examination. The results were evaluated with the intraclass correlation test and both measurements were statistically significantly similar with each other(R = 0.982, p = 0.0001). Dental age (DA) and chronological age (CA) were consistent for boys in the 16-16.9 age group and for girls in the 9-9.9 and 15-15.9 age groups. From this study, we can conclude that dental age varies across ethnic populations. Additionally, dental maturation varies across different regions of the same country. Because Demirjian's standards are not suitable for all age groups of southern Turkish children, a new table is necessary for evaluating this population. Future studies using multi-ethnic population data are needed to establish the international applicability of Demirjian's method. (C) 2014 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.Öğe Assessment of the Relationship Between Bone Mineral Density and Disease Activity in Ankylosing Spondylitis Patients with Osteopenia(Galenos Yayincilik, 2013) Guler, Hayal; Ustun, Nilgun; Bolac, Veli Enes; Yagiz, Abdullah Erman; Mansuroglu, Ayhan; Yengil, Erhan; Turhanoglu, Ayse DicleAim: Ankylosing Spondylitis (AS) is a chronic inflammatory disease. Spinal osteopenia is common in AS, probably due to immobility and local cytokine release. In this study, we evaluated the relationship between bone mineral density and disease activity in Ankylosing Spondylitis patients with osteopenia. Material and Methods: Sixty one AS patients (26F, 35M) were enrolled in this study. The disease duration, morning stiffness, Schober tests, Erythrocyte Sedimentation Rate (ESR) and C Reactive Protein (CRP) were analyzed and recorded. Disease activity was evaluated by Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Bone mineral density (BMD) was measured by using GE/LUNAR DPX PRO equipment. Results: The mean age and disease duration of the patients were 38.67 +/- 10.81 and 7.87 +/- 7.09 year. There was osteopenia in 34 (% 55.7) patients. Spine and femur BMD values of this patients were 1.03 +/- 0.16 and 0.88 +/- 0.09. BMD measurements of 27 (% 44.3) patient were found normally. Spine and femur BMD values of this patients were 1.20 +/- 0.11 and 1.11 +/- 0.15. There was not statistically significant difference between osteopenia and normal group in ESR, CRP, and BASDAI values (p>0.05). There was not correlation between BMD values and ESR, CRP, and BASDAI values in osteopenia group (p>0.05). Conclusion: In our study, we did not find relationship between bone mineral density and disease activity in AS patients with osteopenia.Öğe Association of MicroRNA 211 expression with prognosis in colorectal cancer: A case-control study(Lippincott Williams & Wilkins, 2014) Sumbul, Ahmet Taner; Gogebakan, Bulent; Oztuzcu, Serdar; Yengil, Erhan; Sezer, Ahmet; Aball, Huseyin[Abstract Not Available]Öğe Being a neighbor to Syria: A retrospective analysis of patients brought to our clinic for cranial gunshot wounds in the Syrian civil war(Elsevier Science Bv, 2014) Aras, M.; Altas, M.; Yilmaz, A.; Serarslan, Y.; Yilmaz, N.; Yengil, Erhan; Urfali, B.Objective: Toward the end of 2010, the Arab spring, the waves of revolutionary demonstrations and protests influenced also Syria, where violent clashes turned into a civil war. Hundreds of thousands of people became refugees. The use of excessive force unfortunately culminated in numerous deaths and injuries in many cities. Being the closest city to Aleppo, Damascus and Horns, the biggest cities of Syria, Antioch/Hatay has been the city where initial emergency treatments were performed. For this reason, we examined and retrospectively analyzed the medical records of the patients treated in the clinics of our hospital due to cranial gunshot wounds during the war. Material and methods: The medical records of 186 patients who were injured in the Syrian War and brought to, followed up and treated in the Neurosurgery Clinic of Mustafa Kemal University, Faculty of Medicine in Hatay, a Turkish city on the Syrian border, between April 2011 and June 2013. Results: A total of 186 patients were evaluated in a period of more than 2 years. Of all 91.4% of the patients were adults (male/female: 152/18) and 8.6% of them were pediatric patients (male/female: 14/2). The average age of the patients was 31 years, with an age range of between 2 months and 67 years. According to Glasgow coma score (GCS) of the patients at the time of admission, GCS was 3 in 32 patients (17.2%), between 4 and 7 in 70 patients (37.6%), and between 8 and 15 in 84 patients (45.1%). We observed that the patients with GCS of 4-7 had a significantly lower mortality among the 56 patients treated surgically compared with the 14 patients treated medically. Discussion: Cranial gunshot wounds are responsible for high mortality and morbidity. A multiplicity of factors plays a role on morbidity and mortality. These are the duration of transport, the injury pattern, the velocities of the weapons used, and the Glasgow Coma Scales of the patients at the time of admission. Conclusion: The authors recommend that the patients with cranial gunshot wounds who has GCS of 4-7 should be aggressively treated including surgery as well. We do not recommend surgical treatment for patients with GCS of 3. All our experiences show that treatment of gunshot wounds will continue to be a matter of debate, about which there is more to learn. The data presented in this study will once again demonstrate the seriousness of the event, and will, perhaps, contribute to the peace negotiations to end the war. (C) 2014 Elsevier B.V. All rights reserved.Öğe Bir Üniversite hastanesi jinekoloji polikliniğine başvuran kadınlarda parazitolojik ve sitolojik yöntemlerle Trichomonas Vaginalis araştırılması(2015) Kaya Aycan, Özlem; Şilfeler Benk, Dilek; Özgür, Tümay; Kurt Keskin, Raziye; Hamamcı, Berna; Sefil, Nebihat; Bayazıt, Ahmet; Yengil, ErhanGiriş: Bu çalışmada, Trichomonas vaginalis (T. vaginalis) tanısında vajen arka forniksinden alınan örneklerde parazitolojik ve sitolojik yöntemlerin karşılaştırılması amaçlanmıştır Metod: Kesitsel tanımlayıcı bu çalışmada 2013 yılı Mart-Ağustos aylarında Mustafa Kemal Üniversitesi Tıp Fakültesi Araştırma Hastanesi Jinekoloji Polikliniğine çeşitli nedenlerle başvuran 104 kadın hastada T. vaginalis varlığı parazitolojik ve sitolojik tanı yöntemleri ile araştırılmıştır. T. vaginalis’in parazitolojik tanısında, vajen arka forniksinden alınan örneklerde direkt mikroskobi, giemsa boyama ve Cysteine-Peptone-LiverMaltose besiyerine (CPLM) ekim yaparak kültür yöntem, sitolojik tanısında ise serviks ağzından alınan smear, Papanicolaou (PAPS) boyası ile incelenmiştir. Bulgular: Direkt mikroskobik bakı ile olguların 12 (%11.5)’sinde, giemsa boyamada 12 (%11.5)’sinde, kültür yöntemi ile 14 (%13.4)’ünde T. vaginalis saptanmıştır. Sitolojiye gelen örneklerin ancak 5 (%4.8)’inde parazite rastlanılmıştır. Yapılan istatistiksel değerlendirmede anlamlı bir fark bulunmuştur (p<0.05). Sonuç: Bizim çalışmamız, T. vaginalis’in tanısında parazitolojik yöntemlerin sitolojik yöntemlere oranla daha hassas olduğunu göstermiştir. Bu nedenle, özellikle çok eşli ve sağlık kontrollerinin yetersiz yapıldığı gelişmemiş ülkelerde asemptomatik şikâyetleri olanlar T. vaginalis yönünden taranmalıdır.Öğe Brusellozda Brucellacapt (Immunocapture-agglutination) ve Rose Bengal testlerinin değerlendirilmesi(2015) Yula, Erkan; Toka Özer, Türkan; Köksaldı Motor, Vicdan; Yengil, Erhan; İnci, Melek; Aksoy, Hüseyin; Kılınç, ÇetinAmaç: Bruselloz, Gram negatif bir bakteri olan brusella türlerinin neden olduğu son derece bulaşıcı bir zoonotik hastalıktır. İnsan brusellozunun tanısında çok çeşitli serolojik testler kullanılmaktadır. Brusellozun serolojik tanısında sıklıkla tercih edilen yöntem olan tüp aglütinasyon testi, blokan antikor varlığını tespit edemediğinden yalancı negatif sonuçlara yol açabilmektedir. Bu çalışmada farklı iki test olan Rose Bengal testi (RBT) ve immuncapture- aglütinasyon (Brucellacapt) testi sonuçlarının analiz edilmesi ve bu testlerin kullanılabilirliğinin değerlendirilmesi amaçlanmıştır.Materyal Metod: Çalışmaya, Ağustos 2009 - Ağustos 2011 tarihleri arasında Kızıltepe Devlet Hastanesi mikrobiyoloji laboratuarına çeşitli polikliniklerden gelen 220 hastadan alınan serum örneği dahil edilmiştir. Her bir hasta serumunda hem RBT (ADR Diagnostics, Medico Chemistry) hem de Brucellacapt (ADR Diagnostics, Medico Chemistry) testleri çalışılmıştır. Her iki test de üretici firmanın talimatları doğrultusunda gerçekleştirilmiştir. Brucellacapt testinde 1/160 serum titresi eşik değer olarak kabul edilmiştir. Çalışma grubuna klinik bulgulara dayanarak bruselloz şüphesi olan 220 hasta dahil edilmiştir.Bulgular: Serum örneklerin serolojik olarak incelenmesi ile her iki test 146 (%66,4) hastada negatif bulunurken, hem RBT hem de Brucellacapt testinin pozitif olduğu hasta sayısı ise 59 (%26,8) olarak bulunmuştur. Ek olarak sadece RBT testinin pozitif olduğu hasta sayısı 9 (%4,1), sadece Brucellacapt testinin pozitif olduğu hasta sayısı ise 6 (%2,7) olarak tespit edilmiştir. Toplamda RBT 68 hastada (%30,9), Brucellacapt testi ise 65 hastada (%29,5) pozitif olarak bulunmuştur.Sonuç: Bölgemizde brusellozun endemik bir problem olarak devam ettiği tespit edilmiştir. RBT, bruselloz tanısında, tecrübeli eleman gerektirmeyen, yorumlanması kolay, maliyeti düşük ve teknik olarak da kolay uygulanabilir bir testdir. Brucellacapt testi de kolay ve pratik bir test olup bruselloz tanısında tamamlayıcı bir test olarak kullanılabilir.Öğe Changes of oxidative stress in 3D film to be prepared for echocardiography A randomized controlled study(Lippincott Williams and Wilkins, 2024) Demir, Emel; Duzguner, Vesile; Yilmaz, Nuh; Yengil, ErhanBackground: Echocardiography (ECHO) is a nonprocedure that causes acute stress in children. Fear, anxiety, and fluctuations in children’s blood pressure and heart rate can potentially lead to alterations in echocardiographic measurements. The insufficient research on virtual reality pediatric preparation applications, particularly in the context of echocardiographic procedures, underscores the necessity for additional studies focusing on pediatric patients. This study sought to assess the impact of virtual reality applications tailored explicitly for ECHO on children’s oxidative stress levels. Methods: This was a prospective, randomized, controlled experimental study. Forty-eight children (experimental/24, control/24) aged 7 to 12 years who had an ECHO appointment in the pediatric cardiology outpatient clinic in the 3 months from June to August 2019 participated in the study. Participants whose blood analyses showed hemolysis were eliminated, and the study was completed with 37 children in total: 16 children in the experiment and 21 children in the control. Post hoc power analysis was performed for sample adequacy, and the power of the study was found to be 0.99. A 3D film was prepared for the research and applied to the experimental group before the procedure. All children’s oxidative stress levels (cortisol, malondialdehyde, nitric oxide) and glutathione levels were checked after ECHO. Results: The stress hormone cortisol and malondialdehyde levels were lower in the 3D-applied experimental group than in the control group. As another crucial anti-stress antioxidant factor, glutathione level increased in the experimental group compared to the control group (P < .05). Conclusion: The research revealed that the 3D film used to prepare ECHO reduces the stress parameters associated with heart risk and may affect the ECHO measurements. At the same time, the study also proved the positive effect of 3D film preparation by increasing the anti-stress factor. Copyright © 2024 the Author(s).Öğe Comparison between ultrasound-guided sciatic-femoral nerve block and unilateral spinal anaesthesia for outpatient knee arthroscopy(Sage Publications Ltd, 2013) Davarci, Isil; Tuzcu, Kasim; Karcioglu, Murat; Hakimoglu, Sedat; Ozden, Raif; Yengil, Erhan; Akkurt, Cagla OzbakisObjective To compare unilateral spinal anaesthesia (USA) and ultrasound-guided combined sciatic-femoral nerve block (USFB) in ambulatory arthroscopic knee surgeries in terms of haemodynamic stability, nerve block quality, bladder function, adverse events and time-to-readiness for discharge (TRD). Methods Patients undergoing ambulatory arthroscopic knee surgery were randomly assigned to one of two groups. The USA group received 2ml (10mg) of 0.5% levobupivacaine and the USFB group received a 25ml mixture consisting of 10ml of 2.0% lidocaine, 10ml of 0.5% levobupivacaine and 5ml of saline (15ml for the femoral and 10ml for the sciatic nerve block). Preparation time (PT), surgical anaesthesia time (SAT), operation time, total anaesthesia time, time-to-first spontaneous urination, time-to-first analgesia, TRD, adverse events and patient satisfaction were recorded. Results A total of 40 patients were enrolled in the study (n=20 per group). PT, SAT, total anaesthesia time and time-to-first analgesia were significantly shorter in the USA group than the USFB group; time-to-first spontaneous urination and TRD were significantly longer in the USA group than the USFB group. Conclusions USFB provided sufficient duration of sensory blockade and it reduced the TRD and the rate of adverse events.Öğe The comparison of freehand fluoroscopic guidance and electromagnetic navigation for distal locking of intramedullary implants(Elsevier Sci Ltd, 2013) Uruc, Vedat; Ozden, Raif; Dogramaci, Yunus; Kalacı, Aydıner; Dikmen, Besir; Yildiz, Omer Serkan; Yengil, ErhanIntroduction: In locking intramedullary nails, the most important problem is to put the distal interlocking screw accurately and quickly with minimum radiation exposure. The purpose of this clinical study was to compare the fluoroscopic time and surgical time required for distal locking with either free-hand fluoroscopic guidance or with an electromagnetic navigation system. Materials and methods: The study comprised 54 patients with 58 fractures of the lower extremity. The patients were divided in two groups: distal locking with freehand fluoroscopic guidance (group I) and distal locking with electromagnetic navigation (group II). The primary outcome in this study was fluoroscopy time. The secondary outcome was the operative time in distal interlocking. Results: In group I, the mean operation time was 108 (81-135) min, the mean time for distal interlocking was 18.35 (9-27) min, the total fluoroscopy time was 47.77 (19-74) s, the mean fluoroscopy time during distal interlocking was 18.29 (2-29) s and the mean attempt at number of distal locking for two screws was 9.96 (2-18) times. In group II, the mean operation time was 80.96 (63-100) min, the mean time for distal interlocking was 7.85 (6.5-10) min, the total fluoroscopy time was 22.59 (15-32) s, the mean fluoroscopy time during distal interlocking was 1.62 (0-2) s and the mean attempt number of distal interlocking was 2 (2-2). Conclusion: Fluoroscopy time to achieve equivalent precision is significantly reduced with electromagnetism-based surgical navigation compared with free hand fluoroscopic guidance. Also the operative time is significantly reduced with electromagnetic based navigation. (c) 2012 Elsevier Ltd. All rights reserved.Öğe Comparison of mean platelet volume values between patients with nasal polyp and healthy individuals(2013) Çevik, Cengiz; Yengil, Erhan; Akbay, Ercan; Arlı, Cengiz; Gülmez, Mehmet İhsan; Akoğlu, ErtapAmaç: Nazal Polip (NP) Allerjik Rinit (AR) sıklıkla birlikte görülür. Allerjik hastalarda ateroskleroz riskinde artış olduğu bildirilmektedir. Çalışmamızda aterosklero- zun bir belirteci olarak kullanılan Mean Platelet Volume (MPV) değerlerini nazal polip hastalarında incelemeyi amaçladık. Yöntemler: Nazal polip tanısıyla fonksiyonel endoskopik sinüs cerrahisi (FESC) yapılan 75 hasta değerlendirildi. Aynı yaş grubundan AR şikayeti olmayan sağlıklı 75 bi- reyin verileri kontrol gurubu olarak incelendi. Beyaz kan hücresi (WBC), trombosit (PLT), Hemoglobülin (Hb) ve MPV değerleri ayrı ayrı kaydedildi. Bulgular: MPV değerleri nasal polipli hastalarda 7,89±1,02 fL, kontrol hastalarında 8,32±1,42 fL idi. İstatistiksel olarak anlamlılık tespit edildi. Sonuç: Çalışmamızda sonuç olarak NP hastalarındaki kontrol grubuna oranla MPV değeri düşük tespit edildi.Öğe Comparison of Mean Platelet Volume Values between Patients with Nasal Polyp and Healthy Individuals(Galenos Yayincilik, 2013) Cevik, Cengiz; Yengil, Erhan; Akbay, Ercan; Arli, Cengiz; Gulmez, Mehmet Ihsan; Akoglu, ErtapObjective: Nasal Polyp (NP) and Allergic Rhinitis (AR) are frequently seen in common. It has been reported that there is an increase in the risk of atherosclerosis in allergic patients. In our study, we aimed to evaluate Mean Platelet Volume (MPV) values in patients with NP, which is used as a marker of atherosclerosis. Methods: Seventy-five patients who underwent functional endoscopic sinus surgery (FESS) with a diagnosis of NP were reviewed. Seventy-five age-matched healthy individuals without AR made up the control group. Val-ues of white blood cell (WBC), platelet (PLT), hemoglobilin (Hb) and MPV were evaluated. Results: MPV values were found to be low in patients with NP 7.89 +/- 1.02 fL compared to control group 8.32 +/- 1.42 fL. This finding was statistically significant. Conclusion: It was found that MPV values are significantly low in patients with NP than control group.Öğe DEFINING THE EFFECT OF CHILD LABOUR TRAINING MODULE ON NGO’S ATTITUDES TOWARDS CHILD RIGHTS(Ankara Yildirim Beyazit University, 2020) Demir, Emel; Yengil, ErhanObjectives: Child labour is an interdisciplinary issue including the child rights dimension. Child rights training for non-governmental organizations in the means of forfeiture and keeping the rights of children gives crucial responsibility to NGO leaders. The research is done to assess the change of child rights knowledge level of NGO leaders via training. Materials and Methods: The research is experimental and it is accomplished in 4 pilot cities (Adana, Mersin, Ordu, Manisa) in four months between March and June 2018 and 123 persons took part in it. The study is supported by a UNICEF project cooperation with The Confederation of Turkish Tradesmen and Craftsmen (CTTC) and Hatay Mustafa Kemal University (HMKU). In the frame of the research, the leaders are given a four hours of training on child rights and child labour. Child labour survey form and child rights attitude scale is applied to the leaders before and after the training. The permission for the research is got from HMKU Ethics Committee. Gathered data is analyzed by SPSS 22, examined by Kolmogorov-Smirnow test in the means of distribution and then inter-groups Mann-Whitney U test / Kruskal Wallis test is used. Wilcoxon test is used before and after the training and p>0.05 is accepted as meaningful. Results: As a result of the research findings, child rights scale points average of NGO leaders are 97.52±10.95 before training for preliminary test; and 99.02±10.71 after training for posttest. Acquired values gathered before and after child rights training are statistically meaningful (p=0.01). The effect of training compared to the gender of leaders (M/F), working position (President/Worker), working experience (0-11 years), age variables is not statistically meaningful (p>0.05). On the other hand, education level of leaders is statistically meaningful depending on the cities that the research accomplished. Conclusion: Child rights knowledge level could be increased via the training of NGO leaders. The trainings should be increased considering the regional results depending on the pilot studies. © 2020 by the Author(s).Öğe Defining the effect of child labour training module on NGO’s attitudes towards child rights(Ankara Yıldırım Beyazıt Üniversitesi Tıp Fakültesi, 2020) Demir, Emel; Yengil, ErhanAmaç: Çocuk işçiliği çocuk hakları boyutuyla disiplinler arası çalışılması gereken bir konudur. Sivil toplum örgütlerinin Çocuk hakları konusunda eğitimi, çocuk işçiliğindeki çocukların hak kaybı ya da hakların korunması yönünde sivil toplum liderlerine önemli sorumluluk vermektedir. Araştırma sivil toplum örgütü liderlerinin çocuk hakları konusunda bilgi düzeyinin eğitim ile değişimini değerlendirmek amacıyla yapılmıştır. Materyal ve Metot: Araştırmanın tipi deneyseldir. Araştırma 2018 yılı Mart- Haziran ayları arasında 4 ayda, pilot olarak seçilen 4 ilde (Adana, Mersin, Ordu, Manisa) yapılmış, araştırmaya 123 kişi katılmıştır. Bu araştırma, Türkiye Esnaf Sanatkarlar Konfederasyonu (TESK) ve Mustafa Kemal Üniversitesi işbirliği ile UNICEF projesi kapsamında desteklenmiştir. Araştırma için liderlere, çocuk hakları ve çocuk işçiliği konusunda 4 saatlik bir eğitim verilmiştir. Bu eğitim öncesi ve sonrasında liderlere çocuk işçiliği anket formu ve çocuk hakları tutum Ölçeği uygulanmıştır. Araştırma izni MKÜ Etik kurulundan alınmıştır. Veriler SPSS 22 de analiz edilmiş, dağılım yönünden Kolmogorov-Smirnow testi ile incelenmiş sonrasında ise gruplar arası MannWhitney U testi / Kruskal Wallis testi kullanılmıştır. Eğitim öncesi ve sonrası için ise Wilcoxon testi ile değerlendirilmiş olup, p>0.05 anlamlı kabul edilmiştir. Bulgular: Araştırma sonuçlarına göre sivil toplum liderlerinin çocuk hakları ölçeği puan ortalaması eğitim öncesi ön-test 97.52±10.95, eğitim sonrası son-test 99.02±10.71 olarak bulunmuştur. Çocuk haklarına yönelik eğitim öncesi ve sonrası değerler istatiksel olarak anlamlıdır (p=0.01). Eğitimin, liderlerin cinsiyeti (E/K), iş pozisyonu (Başkan/Çalışan), iş yılı tecrübesi (0-11 yıl), yaş değişkenlerine göre etkisi istatiksel olarak anlamlı değildir (p>0.05). Fakat eğitim, liderlerin eğitim durumu ve çalışmanın yapıldığı illere göre istatiksel olarak anlamlı bulunmuştur (p<0.05). Sonuç: Çocuk hakları bilgi düzeyi, sivil toplum örgütleri liderlerinin eğitim ile yükseltilebilir. Eğitimler pilot çalışmalara göre, bölgesel sonuçlar dikkate alınarak artırılmalıdır.Öğe Deli bal ile zehirlenen bir aile : Olgu sunumu(2013) Yengil, Erhan; Akhan, Mehmet Masuk; Yengil, Duygu; Öztürkoğlu, Hüseyin Evren; Şilfeler, İbrahim; Karakuş, AliDeli bal zehirlenmesi, “Rhododendron ponticum” ve “Rhododen- dron luteum” çiçeklerinden beslenen arıların üretti¤i, grayanotoksin içeren balın tüketilmesiyle oluşmaktadır. Dünyada Nepal, Kuzey Amerika, Brezilya ve Japonya’da, ülkemizde ise Do¤u Karadeniz böl- gesinde görülmektedir. Deli bal tüketimiyle oluşan zehirlenmelerde toksisite semptomları, az miktarda bal alımı ile bile gelişebilmektedir. Bu çalışmada, acil servise başvuran 35 yaşındaki anne ve 38 yaşında- ki baba ile bunların 5 ve 10 yaşlarında iki kız çocuklarında görülen deli bal zehirlenmesi aile olgusu sunuldu. Anne ve babada baş dön- mesi, bulantı-kusma, fenalaşma hissi ve karın a¤rısı, çocuklarda ise hafif bulantı ve halsizlik şikâyetleri vardı. Her iki ebeveynde bradikar- di ve hipotansiyon gözlenmesi üzerine bal yeme öyküsü araştırıldı ve sabah kahvaltıda bal yedikleri ö¤renildi. Bu olgu sunumunda birçok hastalıkla karışabilen deli bal zehirlenmesinin teşhis ve tedavisinin gözden geçirilmesi amaçlanmıştır.Öğe Demodex folliculorum in polycystic ovary syndrome patients(Verduci Publisher, 2015) Silfeler, D. Benk; Kurt, R. Keskin; Kaya, O. A.; Yengil, Erhan; Hamamci, B.; Okyay, A. G.; Beyazit, A.OBJECTIVE: In this study, we aimed to investigate frequency of Demodex (D.) folliculorum infestation in Polycystic Ovary Syndrome patients. PATIENTS AND METHODS: The study population consisted of 30 PCOS patients and 30 matched healthy control subjects admitted to the Hospital of Mustafa Kemal University, Gynecology and Obstetrics Clinic between March 2013 and January 2014. The demographic characteristics of the patients were recorded. Samples from the face region of the subjects were taken by standard method of superficial skin biopsy and evaluated by microscopy. Presence of five or more D. species in a cm(2) was considered as positive. RESULTS: There were no significant differences in age, body mass index, diabetes mellitus incidence between PCOS patients and the control group. However, D. folliculorum infestation was found to increased in PCOS patients (n = 9; 30%) when compared to the control group (n = 2; 6, 7%) (p: 0.04). CONCLUSIONS: Our study results revealed that Demodex folliculorum appearance increased in PCOS patients.Öğe DEMOGRAPHIC, CLINIC AND LABORATORY CHARACTERISTICS OF CASES PRESENTED TO EMERGENCY DEPARTMENT WITH SCORPION STING: 345 CASES OVER A 4-YEARS PERIOD(Carbone Editore, 2013) Duru, Mehmet; Karakus, Ali; Yengil, Erhan; Sahan, Mustafa; Zeren, Cem; Kekec, Zeynep; Yagiz, Abdullah ErmanIntroduction: In the scorpion stings, based on the involved system, clinical and laboratory changes may be seen in a wide spectrum from mild pain and flushing to death. The present study was aimed to assess patient demographics, clinical characteristics and outcomes. Methods:All patients presented to emergency department with scorpion sting between 2008 and 2011 were retrospectively evaluated by using electronic database. Results: Overall, 345 cases were included into the study, consisting of 160 male (46.4%) and 185 female (53.6%) with a mean age of 34.39 +/- 19.47 years. It was found that scorpion sting patients were most commonly stung at extremities (n=322; 93.3%). The most commonly observed complaint was pain (n=334; 96.8%).Localized flushing and edema were observed in 307 cases (89.0%). In the laboratory evaluation, it was found that mean values of complete blood counts, biochemistry assays and prothrombin time (PT). international normalized ratio (INR) and partial thromboplastin time (PTT) were within normal range. Of the cases, 99.4%(n=343) were discharged, while two children (0.6%) died due to cardiac and respiratory complications. Conclusions: Since complete blood count and coagulation assays may be normal, these assays aren't routinely needed in all cases with scorpion sting. Anti-serum therapy should be considered at early course of the disease in children and elderly patients due to complications and mortality; it should be intravenously administered V indicated, but it should not be used in all patients.Öğe Demographic, clinic and laboratory characteristics of cases presented to emergency department with scorpion sting: 345 cases over a 4-years period(Acta Medica Mediterranea, 2013) Duru, Mehmet; Karakus, Ali; Yengil, Erhan; Sahan, Mustafa; Zeren, Cem; Kekec, Zeynep; Yagiz, Abdullah ErmanIntroduction: In the scorpion stings, based on the involved system, clinical and laboratory changes may be seen in a wide spectrum from mild pain and flushing to death. The present study was aimed to assess patient demographics, clinical characteristics and outcomes. Methods:All patients presented to emergency department with scorpion sting between 2008 and 2011 were retrospectively evaluated by using electronic database. Results: Overall, 345 cases were included into the study, consisting of 160 male (46.4%) and 185 female (53.6%) with a mean age of 34.39±19.47 years. It was found that scorpion sting patients were most commonly stung at extremities (n=322; 93.3%).The most commonly observed complaint was pain (n=334; 96.8%).Localized flushing and edema were observed in 307 cases (89.0%). In the laboratory evaluation, it was found that mean values of complete blood counts, biochemistry assays and prothrombin time (PT), international normalized ratio (INR) and partial thromboplastin time (PTT) were within normal range. Of the cases, 99.4%(n=343) were discharged, while two children (0.6%) died due to cardiac and respiratory complications. Conclusions: Since complete blood count and coagulation assays may be normal, these assays aren't routinely needed in all cases with scorpion sting. Anti-serum therapy should be considered at early course of the disease in children and elderly patients due to complications and mortality; it should be intravenously administered if indicated, but it should not be used in all patients.Öğe Descriptive epidemiology of non-hodgkin's lymphomas in Hatay(2013) Özgür, Tümay; Yaldiz, Mehmet; Kaya, Hasan; Yengil, Erhan; Toprak, SerhatThe incidence of Non-Hodgkin's Lymphomas (NHL) varies among different parts of the world. NHL are the 12th most common cancer in Europe and increasing dramatically during the last years. In this study, it was aimed to analyse the descriptive epidemiology of NHL in Hatay region with retrospective archieve datas. One hundred and thirty-three NHL cases between 2005 and 2013 have been reviewed retrospectively in the Pathology Department of the Mustafa Kemal University. All of the cases were classified according to World Health Organization modified in 2008. Eighty-two (61.7%) cases were male and 51 (38.3%) cases were female. Ninety-two of the cases (69.2%) were nodal lymphoma, and the remaining 41 (30.8%) were extranodal lymphoma. The most common extranodal involvement regions were tonsils and nasopharynx with frequencies of 21.9% (9) and 19.5% (8), respectively. The age distribution pattern revealed that NHL were mostly diagnosed in the ages of 41-65 years in nodal (41.3%) and extranodal sited NHL groups (53.6%). The most frequent NHL was diffuse large cell B cell lymphoma (50.4%) and chronic lymphocytic leukemia/small lymphocytic lymphoma (17.3%). Our results were similar with the literature. Further epidemiologic studies with larger series defining the profile of NHL subtypes may be more worthy.Öğe Determination of hearing levels in patients with Familial Mediterranean Fever(2013) Cevik, Cengiz; Silfeler, Ibrahim; Arica, Vefik; Yengil, Erhan; Akbay, Ercan; Sarac, Tuba; Basarslan, FatmagulObjective: Familial Mediterranean Fever is the most common congenital, periodic fever condition that affects over 100,000 people worldwide. In the literature, there is limited number of studies about hearing levels in children with Familial Mediterranean Fever. In the present study, we aimed to investigate hearing levels and cochlear functions by using Distortion product Otoacoustic Emission and High Frequency Audiometry (250-20,000. Hz) in pediatric patients with Familial Mediterranean Fever. Methods: The study included 62 children with Familial Mediterranean Fever and 27 healthy children with similar age and gender. After otoscopic examination, both groups underwent audiological evaluation including High Frequency Audiometry (250-20,000. Hz) and Distortion product Otoacoustic Emissions. The results obtained were assessed among groups. In addition, these results were compared regarding colchicine use, age at the onset of disease and duration of the diseases in the Familial Mediterranean Fever group. Results: Of the Familial Mediterranean Fever patients, 93.5% were on colchicine therapy and mean duration of colchicine use was 19.9 ± 13.9 months. The mean age at diagnosis was 6.57 ± 2.86 years (min-max: 2-14) and mean duration of disease was 23 ± 17 months (min-max: 6-84). Pure tone audiometry values, and hearing levels between 9000 and 20,000. Hz were similar and within normal range in both groups. The Distortion product Otoacoustic Emissions responses at the frequencies of 1020, 2040, 3000, 4080 and 5040. Hz were similar for both groups. Conclusion: To the best of our knowledge, this is the first study evaluating hearing levels at the frequencies of 18. kHz and 20. kHz in children with Familial Mediterranean Fever in the literature. In children with Familial Mediterranean Fever, Pure tone audiometry values, hearing values obtained at all frequencies from 250 to 20,000. Hz, and Distortion product Otoacoustic Emissions levels were within normal range. Furthermore, hearing levels were found to be similar to those in healthy children. © 2013 Elsevier Ireland Ltd.