Varicella Zoster Virus Pneumonia without Signs of Vesicular Skin and Mucosa Lesions During Pregnancy
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Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bilimsel Tip Yayinevi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Chickenpox is an infectious disease caused by the varicella zoster virus (VZV). VZV causes two different clinical pictures, chickenpox and shingles. Chickenpox is a preventable, benign disease with a vesicular rash, but it can cause life-threatening organ involvement such as pneumonia. Pneumonia is more common and dangerous in pregnant women. The importance of history and clinical findings in diagnosis is indisputable. Isolation of VZV from vesicular fluid is the gold standard in laboratory diagnosis. From body fluids, detection of VZV nucleic acid by Polymerase Chain Reaction (PCR) and antigen by Direct Immunofluorescent antibody (DFA) is sensitive and specific. Detection of IgM and IgG by serological methods such as Enzyme-Linked Immunosorbet Assay (ELISA), Enzyme Linked Florencent assay (ELFA) is used for diagnosis. In severe and atypical cases, RT-PCR is the appropriate method to rapid demonstration of VZV. Demonstrating VZV IgM and IgG positivity with serological methods such as ELISA and ELFA is also important for the diagnosis of acute chickenpox. Reducing complications, antiviral treatment and supportive treatment are the cornerstones of chickenpox management. Here, we wanted to share a pregnant case who had not had chickenpox/shingles before, had no history of contact with chickenpox, had not been vaccinated against chickenpox, and developed pneumonia due to varicella without skin and mucous membrane involvement.
Açıklama
Anahtar Kelimeler
Pregnancy, Chickenpox infection, Varicella pneumonia, Varicella zoster virus
Kaynak
Flora Infeksiyon Hastaliklari Ve Klinik Mikrobiyoloji Dergisi
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
28
Sayı
3
