Intra-day changes in the levels of biochemistry parameters

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dc.contributor.authorArpacı, Abdullah
dc.contributor.authorDoğan, Serdar
dc.contributor.authorGül, Bahar Ünlü
dc.contributor.authorKuş, Berna
dc.contributor.authorDırıcan, Emre
dc.date.accessioned2024-09-19T16:21:01Z
dc.date.available2024-09-19T16:21:01Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjectives: People mostly live in the nonfasting state during a normal 24-h cycle. This study aims to compare the levels of\r18 biochemical parameters during different hours of the day.\rMethods: A total of 18 biochemical tests of patients who visited outpatient clinics only once between January 1, 2010,\rand December 31, 2019, were evaluated at the Hatay Mustafa Kemal University (HMKU) Central Laboratory by using\rhospital database information. The tests are albumin (Alb), aspartate aminotransaminase (AST), alanine aminotransaminase\r(ALT), alkaline phosphatase (ALP), amylase, blood urea nitrogen (BUN), calcium (Ca), total cholesterol (TC), creatine\rkinase (CK), creatinine (Cr), gamma-glutamyltransferase (GGT), glucose, high-density lipoprotein cholesterol\r(HDL-C), inorganic phosphorus (Pi), iron (Fe), total protein (TP), triglyceride (TG), and lipase. The blood samples of the\rpatient were divided into eight groups according to their collection time as follows: (a) 07:00-07:59, (b) 08:00-08:59, (c)\r09:00-09:59, (d) 10:00-10:59, (e) 11:00-11:59, (f ) 12:00-13:59, (g) 14:00-14:59, and (h) 15:00-17:00.\rResults: A statistically significant difference was found between the groups in terms of all parameters except amylase,\rGGT, and TP (p<0.05). The effect size refers to the minimum amount of difference that is clinically significant. According\rto the effect size values, there was no significant difference between time groups in the following parameters: Alb, ALT,\rAST, Pi, Ca, TC, Cr, Fe, glucose, BUN, lipase, TG, ALP, HDL-C, and CK (?<0.30).\rConclusion: When considering all of the results, nonfasting screening would not only be acceptable but also make\rphysiologic sense.en_US
dc.identifier.doi10.14744/ijmb.2022.54227
dc.identifier.endpage108en_US
dc.identifier.issn2587-2362
dc.identifier.issn2618-642X
dc.identifier.issue2en_US
dc.identifier.startpage101en_US
dc.identifier.trdizinid521089en_US
dc.identifier.urihttps://doi.org/10.14744/ijmb.2022.54227
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/521089
dc.identifier.urihttps://hdl.handle.net/20.500.12483/15528
dc.identifier.volume5en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofInternational Journal of Medical Biochemistryen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleIntra-day changes in the levels of biochemistry parametersen_US
dc.typeArticleen_US

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