Patients with first episode psychosis and chronic schizophrenia may not differ in mean platelet volume affecting its value as an indicator of cardiovascular disease
Yükleniyor...
Dosyalar
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Psikofarmakoloji Derneği
Erişim Hakkı
info:eu-repo/semantics/openAccess
Attribution 3.0 United States
Attribution 3.0 United States
Özet
Objective: The aim of the present study was to examine differences in terms of mean platelet volume (MPV) in patients with
first episode psychosis, chronic schizophrenia, and psychiatrically healthy controls and to determine the potential value of
MPV for cardiovascular disorders in patients with psychotic disorders.
Methods: A total number of 32 patients with first episode psychosis, 44 patients with chronic schizophrenia, and 43 randomly
selected weight- and body mass index-matched psychiatrically healthy controls who presented to the Psychiatry Outpatient
Clinic were included. The Positive and Negative Syndrome Scale (PANSS) was administered to the patients group. The body
mass index (BMI) was calculated and MPV was measured for each subject.
Results: The mean MPV level was 9.38±1.00 fL in patients with first episode psychosis, 9.60±1.02 fL in patients with chronic
schizophrenia, and 9.2±0.94 fL in psychiatrically healthy controls group. MPV levels were not significantly different between
the three groups. There were no statistically significant differences between the three groups in terms of platelet count or
BMI. There were no statistically significant correlations between the MPV levels and total PANSS scores in the patients groups.
Conclusions: To the best of our knowledge, the present study was the first to evaluate the MPV levels in patients with first
episode psychosis. We consider that it is not appropriate for MPV to be used as an indicator for CVDs in patients with psychosis.
Better-designed and more advanced studies are necessary to determine the exact function of platelets and the importance of
MPV in patients with first episode psychosis and chronic schizophrenia.
Açıklama
Anahtar Kelimeler
Chronic schizophrenia, First attack psychosis, Mean platelet volume
Kaynak
Psychiatry and behavioral sciences
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
9
Sayı
4
Künye
Sahpolat, M., & Ari, M. (2019). Patients with First Episode Psychosis and Chronic Schizophrenia may not Differ in Mean Platelet Volume Affecting its Value as an Indicator of Cardiovascular Disease. Sciences, 9(4), 166-171.
