Patients with first episode psychosis and chronic schizophrenia may not differ in mean platelet volume affecting its value as an indicator of cardiovascular disease

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dc.authorid0000-0002-0022-2389en_US
dc.authorid0000-0002-8003-1661en_US
dc.contributor.authorŞahpolat, Musa
dc.contributor.authorArı, Mustafa
dc.date.accessioned2020-09-01T07:33:40Z
dc.date.available2020-09-01T07:33:40Z
dc.date.issued2019en_US
dc.departmentTayfur Ata Sökmen Tıp Fakültesien_US
dc.description.abstractObjective: The aim of the present study was to examine differences in terms of mean platelet volume (MPV) in patients with first episode psychosis, chronic schizophrenia, and psychiatrically healthy controls and to determine the potential value of MPV for cardiovascular disorders in patients with psychotic disorders. Methods: A total number of 32 patients with first episode psychosis, 44 patients with chronic schizophrenia, and 43 randomly selected weight- and body mass index-matched psychiatrically healthy controls who presented to the Psychiatry Outpatient Clinic were included. The Positive and Negative Syndrome Scale (PANSS) was administered to the patients group. The body mass index (BMI) was calculated and MPV was measured for each subject. Results: The mean MPV level was 9.38±1.00 fL in patients with first episode psychosis, 9.60±1.02 fL in patients with chronic schizophrenia, and 9.2±0.94 fL in psychiatrically healthy controls group. MPV levels were not significantly different between the three groups. There were no statistically significant differences between the three groups in terms of platelet count or BMI. There were no statistically significant correlations between the MPV levels and total PANSS scores in the patients groups. Conclusions: To the best of our knowledge, the present study was the first to evaluate the MPV levels in patients with first episode psychosis. We consider that it is not appropriate for MPV to be used as an indicator for CVDs in patients with psychosis. Better-designed and more advanced studies are necessary to determine the exact function of platelets and the importance of MPV in patients with first episode psychosis and chronic schizophrenia.en_US
dc.identifier.citationSahpolat, M., & Ari, M. (2019). Patients with First Episode Psychosis and Chronic Schizophrenia may not Differ in Mean Platelet Volume Affecting its Value as an Indicator of Cardiovascular Disease. Sciences, 9(4), 166-171.en_US
dc.identifier.doi10.5455/PBS.20190515091832en_US
dc.identifier.endpage171en_US
dc.identifier.issn2146-1473
dc.identifier.issn2636-834X
dc.identifier.issue4en_US
dc.identifier.startpage166en_US
dc.identifier.trdizinid345012en_US
dc.identifier.urihttps://dx.doi.org/10.5455/PBS.20190515091832
dc.identifier.urihttps://hdl.handle.net/20.500.12483/2983
dc.identifier.volume9en_US
dc.identifier.wosWOS:000640975000003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherPsikofarmakoloji Derneğien_US
dc.relation.ispartofPsychiatry and behavioral sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Başka Kurum Yazarıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectChronic schizophreniaen_US
dc.subjectFirst attack psychosisen_US
dc.subjectMean platelet volumeen_US
dc.titlePatients with first episode psychosis and chronic schizophrenia may not differ in mean platelet volume affecting its value as an indicator of cardiovascular diseaseen_US
dc.typeArticleen_US

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